22883-27-8

Basic information

• Product Name: 2-Propen-1-one, 3-(1H-indol-3-yl)-1-phenyl-
• CAS NO: 22883-27-8
• Molecular Formula: C17H13NO
• Molecular Weight: 247.296
• Mol File: 22883-27-8.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 3-(1H-indol-3-yl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 3-(1H-indol-3-yl)-1-phenyl-(22883-27-8)
• EPA Substance Registry System: 2-Propen-1-one, 3-(1H-indol-3-yl)-1-phenyl-(22883-27-8)

Safety Data

• Hazardous Substances Data: 22883-27-8(Hazardous Substances Data)

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 98-86-2 acetophenone 
• 13993-17-4 3-(1H-indol-3-yl)-1-phenylpropan-1-one 
• 120-72-9 indole 
• 768-03-6 Phenyl vinyl ketone 
• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 

Downstream Products

• 119549-92-7 3-(3-indolyl)-3-(1,2,4-triazol-1-yl)-1-phenyl-propan-1-one 
• 1233334-60-5 4-(1H-indol-3-yl)-7,7-dimethyl-2-phenyl-4,6,7,8-tetrahydroquinolin-5(1H)-one 
• 1330579-01-5 (E)-3-(1H-indol-3-yl)-1,5-diphenylpent-4-en-1-one 
• 1018817-79-2 3-(2-methyl-5-phenyl-3,4-dihydro-2H-pyrazol-3-yl)-1H-indole 
• 140472-56-6 4-methyl-3-(1'-methylindol-3'-yl)-4-nitro-1-phenylpentan-1-one 
• 140472-62-4 5,5-dimethyl-4-(1'-methylindol-3'-yl)-2-phenyl-1-pyrroline 1-oxide 
• 140472-63-5 5,5-dimethyl-4-(1'-methylindol-3'yl)-2-phenyl-1-pyrroline 

Relevant articles and documents

A new method for the synthesis of chalcone derivatives promoted by PPh3/I2under non-alkaline conditions

A straightforward and general method has been developed for the synthesis of chalcone derivatives by a Claisen-Schmidt reaction in the presence of PPh3/I2 in 1,4-dioxane under reflux temperatures. With the condensation of the aromatic ketone and aldehyde occurring at non-strongly alkaline conditions, our proposed method significantly expands the range of applicable substrates, especially for groups that are unstable under alkaline conditions.

Synthesis, docking, and evaluation of novel thiazoles for potent antidiabetic activity

In this study, a series of novel substituted pyrazoles containing indole and thiazole motifs were synthesized and evaluated for their antihyperglycemic activity against α-amylase and α-glucosidase enzymes. Among them, 2-(5-(1H-indol-3-yl)-3-phenyl-1H-pyra

Synthesis and evaluation of chalcone derivatives as novel sunscreen agent

Ultraviolet (UV) irradiation is a serious problem for skin health thus the interest in the research to develop sunscreen agent has been increasing. Chalcone is a promising compound to be developed as its chromophore absorbs in the UV region. Therefore, in

Alpha,beta-unsaturated ketone derivatives, preparation method of derivatives and application of derivatives as medicines

The invention relates to the technical field of medicine, and proposes alpha,beta-unsaturated ketone derivatives and a preparation method thereof. The derivatives have a structural general formula represented by a formula I shown in the specification, whe