22913-26-4Relevant articles and documents
A New Indirect Application of Aggregative Activation: Synthesis of Esters by Cobalt-Catalyzed Carbonylation of Aryl, Heterocyclic, and Vinyl Halides under Atmospheric Pressure
Marchal, Joel,Bodiguel, Jacques,Fort, Yves,Caubere, Paul
, p. 8336 - 8340 (2007/10/02)
Sun lamp illuminated alkoxycarbonylation of aryl, heteroaryl, and vinyl halides was performed under atmospheric pressure of CO in the presence of a cobalt catalyst in situ generated from Co(OAc)2.Illunination through a Pyrex flask was sufficient to catalyze the reaction.This process avoids the use of Co2(CO)8 and excess CH3I, which were required in the earlier procedure.A SRN1 mechanism is proposed.
SYNTHESIS OF 4-CARBOXY-2-THIABICYCLOHEPTAN-6-ONES VIA 3-CARBOXY-2,3-DIHYDROTHIOPHENES: POTENTIAL β-LACTAMASE INHIBITORS
Lange, Gerald,Savard, Marc E.,Viswanatha, Thammaiah,Dmitrienko, Gary I.
, p. 1791 - 1794 (2007/10/02)
3-Carboalkoxy-2,3-dihydrothiophenes, available by Birch reduction of thiophene-3-carboxylic acid or more efficiently by deconjugation of 2,5-dihydrothiophene-3-carboxylic acid by reaction with ethyl chloroformate and triethylamine, undergo cycloaddition reactions with dichloroketene leading to 4-carboxy-7,7-dichloro-2-thiabicycloheptan-6-ones which are of interest as potential β-lactamase inhibitors.