22915-82-8Relevant academic research and scientific papers
Synthesis and antibacterial activity of some novel bis-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and bis-4-thiazolidinone derivatives from terephthalic dihydrazide
Palekar, Vikrant S.,Damle, Amey J.,Shukla
experimental part, p. 5112 - 5116 (2010/02/27)
A novel series of 1,4-bis(6-(substituted phenyl)-[1,2,4]-triazolo[3,4-b]-1,3,4-thiadiazoles (5a-b) and 4-bis(substituted phenyl)-4-thiazolidinone derivatives (7a-c) have been synthesized from terephthalic dihydrazide (1) through multistep reaction sequence. 1,4-Bis(5-aryl-1,3,4-oxadiazole-2yl) benzene derivatives (2a-f) and bis-substituted terephthalohydrazide (6a-e) were also synthesized from terephthalic dihydrazide by cyclization with various aromatic acids and aldehydes. Terephthalic dihydrazide (1) was obtained from poly(ethylene terephthalate) waste from reaction with hydrazine hydrate in good yield (86%). All the synthesized compounds were screened for their antibacterial activities against various bacteria and fungi strains. Several of these compounds showed potential antibacterial activity.
Novel syntheses of symmetrical 2,5-diaryl-1,3,4-oxadiazoles and 1,4-phenylenebis-1,3,4-oxadiazoles
Belen'kii,Luiksaar,Poddubnyi,Krayushkin
, p. 2238 - 2245 (2007/10/03)
The reactions of trichloromethylarenes with excess hydrazine hydrate in ethanol gives symmetrical 2,5-diaryl-1,3,4-oxadiazoles in 68-96% yields. The reaction of 1,4-bis(trichloromethyl)benzene with acylhydrazines in an ethanol-pyridine mixture gives the corresponding substituted or unsubstituted 1,4-phenylenebis-1,3,4-oxadiazoles in 35-51% yields. The mass spectra of 2,5-diaryl-1,3,4-oxadiazoles and 1,4-phenylenebis-1,3,4-oxadiazoles were studied.
An Improved Synthesis of 1,3- and 1,4-Bisbenzenes via Oxidation of Bis-aroylhydrazones of Iso- and Terephthalaldehyde with Lead(IV) Acetate
Rekkas, Stavros A.,Rodios, Nestor A.,Alexandrou, Nicholas E.
, p. 411 - 413 (2007/10/02)
The oxidation of bis-aroylhydrazones of iso- and terephthalaldehyde with lead(IV) acetate leading to 1,3- and 1,4-bisbenzenes is described.
