22934-13-0

Basic information

• Product Name: 2(1H)-pyridinone, 4,6-dimethyl-3-nitro-
• Synonyms: 2(1H)-pyridinone, 4,6-dimethyl-3-nitro-;4,6-dimethyl-3-nitropyridin-2(1H)-one;4,6-Dimethyl-2-nitro(1H)-pyridone;4,6-dimethyl-3-nitro-1H-pyridin-2-one;4,6-dimethyl-3-nitro-2-pyridone;ZERO/004565;ZINC04342603
• CAS NO: 22934-13-0
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168.15
• Mol File: 22934-13-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Acetonitrile (Slightly), DMSO (Slightly)
• CAS DataBase Reference: 2(1H)-pyridinone, 4,6-dimethyl-3-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-pyridinone, 4,6-dimethyl-3-nitro-(22934-13-0)
• EPA Substance Registry System: 2(1H)-pyridinone, 4,6-dimethyl-3-nitro-(22934-13-0)

Safety Data

• Hazardous Substances Data: 22934-13-0(Hazardous Substances Data)

Usage

General Description

4,6-dimethyl-3-nitro-2(1H)-pyridinone is a chemical compound that is characterized by its molecular structure, which includes a pyridinone ring with two methyl groups and a nitro group attached at specific positions. It is commonly used in the pharmaceutical industry as a starting material or intermediate in the synthesis of various pharmaceuticals and agrochemicals. 2(1H)-Pyridinone, 4,6-dimethyl-3-nitro- has potential applications as a building block in the production of drugs and other bioactive compounds due to its unique chemical properties and reactivity. Additionally, it is also used as a research tool in the field of organic chemistry for the development of new synthetic methodologies and strategies. Overall, 4,6-dimethyl-3-nitro-2(1H)-pyridinone plays a significant role in the advancement of drug discovery and chemical synthesis.

Upstream product

• 626-35-7 nitroacetic acid ethyl ester 
• 123-54-6 acetylacetone 
• 64-19-7 acetic acid 
• 14011-21-3 2-nitroacetamide 
• 26163-29-1 2-nitroacetamide ammonium salt 
• 22934-22-1 3-Nitro-6-amino-2,4-dimethyl-pyridin 
• 5407-87-4 2-Amino-4,6-dimethylpyridine 
• 16115-08-5 6-Hydroxy-2,4-lutidin 

Downstream Products

• 89793-09-9 2-chloro-3-nitro-4,6-dimethyl-pyridine 
• 143708-29-6 3-amino-4,6-dimethylpyridin-2(1H)-one 
• 415907-63-0 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethylamine 
• 415907-59-4 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethyl propionate 
• 415907-60-7 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethanol 
• 415907-61-8 3-[4-(2-chloroethyl)phenyl]-2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine 
• 415907-57-2 2-{4-[(4,6-dimethyl-3-nitro-2-pyridinyl)amino]phenyl}ethanol 
• 415907-58-3 2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl}ethanol 
• 415902-95-3 2-ethyl-5,7-dimethyl-3-(4-{2-[({[(4-methylphenyl)sulfonyl]amino}carbonyl)amino]ethyl}phenyl)-3H-imidazo[4,5-b]pyridine 
• 312517-65-0 1,4,6-trimethyl-3-nitro-1H-pyridin-2-one 

Relevant articles and documents

Phenacylation of 6-methyl-beta-nitropyridin-2-ones and further heterocyclization of products

Reaction between the derivatives of 6-methyl-beta-nitropyridin-2-one and phenacyl bromides was studied, and the yields observed were extremely low. The pyridones were converted via chloropyridines to methoxyderivatives, which were N-phenacylated. N-Phenacyl derivatives of 4,6-dimethyl-5-nitropyridin-2-one under the action of base gave 5-hydroxy-8-nitroindolizine and under acidic conditions gave 5-methyl-6-nitrooxazole[3,2-a]pyridinium salt, which underwent recycization with MeONa to 5-methoxy-8-nitroindolizine.

CRYSTAL FORMS OF AN IMIDAZOLE DERIVATIVE

The invention relates to the essentially pure Λ/-[({2-[4-(2-Ethyl-4,6-dimethyl-1 H- imidazo[4,5-c]pyridin-1 -yl)phenyl]ethyl}amino)carbonyl]-4- methylbenzenesulfonamide Polymorph Forms A and B and to processes for the preparation of, compositions containi

Use of EP4 receptor ligands in the treatment of IL-6 involved diseases

Methods of treating IL-6 involved diseases with EP4 receptor ligands, including EP4 receptor antagonists. Assays to determine the effect of test compounds on PGE2-induced whole blood cells activation.