22934-35-6

Upstream product

• 1450-75-5 5-Bromo-2-hydroxyacetophenone 
• 97-94-9 triethyl borane 
• 99-58-1 3-bromo-4-methoxybenzoic acid 
• 1927-95-3 4-bromophenyl acetate 
• 90-00-6 o-Hydroxyethylbenzene 
• 29643-34-3 1-(3-ethyl-4-methoxyphenyl)ethan-1-one 
• 124-38-9 carbon dioxide 
• 33839-11-1 4-bromo-2-ethyl-1-methoxybenzene 
• 18980-21-7 4-bromo-2-ethylphenol 

Downstream Products

• 220844-12-2 1-(3-ethyl-4-methoxyphenyl)-3-quinolin-4-ylurea hydrochloride 
• 22934-36-7 methyl 3-ethyl-4-hydroxybenzoate 
• 95763-98-7 2-Aethyl-4-methoxycarbonyl-cyclohexanol 

Relevant academic research and scientific papers

B-Alkyl Suzuki-Miyaura cross-coupling of tri-n-alkylboranes with arylbromides bearing acidic functions under mild non-aqueous conditions

An efficient and chemoselective Pd-catalyzed B-alkyl Suzuki-Miyaura cross-coupling of tri-n-alkylboranes with arylbromides possessing acidic functions is described. This protocol features the relatively weak base Cs2CO3 and mild non-

Direct B-alkyl Suzuki-Miyaura cross-coupling of trialkyl-boranes with aryl bromides in the presence of unmasked acidic or basic functions and base-labile protections under mild non-aqueous conditions

An efficient and chemoselective palladium-catalyzed direct B-alkyl Suzuki-Miyaura cross-coupling of trialkylboranes with diversely functionalized aryl bromides is described. A wide variety of unmasked acidic or basic functions are tolerated. The mild non-

Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia

This invention provides compounds of Formula I having the structure E is S, SO, SO2, O, or NR1c; X is hydrogen, halogen, alkyl of 1-6 carbon atoms, alkenyl of 2-7 carbon atoms, CN, aryl, aralkyl of 6-12 carbon atoms, hydroxyalkyl of 1-6 carbon atoms, hydroxyaralkyl of 6-12 carbon atoms, perfluoroalkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, aryloxy; arylalkoxy, nitro, amino, NR2R2a, NR2COR2a, cycloalkylamino of 3-8 carbon atoms, morpholino, alkylsulfanyl of 1-6 carbon atoms, arylsulfanyl, pyridylsulfanyl, 2-N,N-dimethylaminoethylsulfanyl, —OCH2CO2R2bor —COR2c; Z1and Z2are each, independently, hydrogen, halogen, CN, alkyl of 1-6 carbon atoms, aryl, aralkyl of 6-12 carbon atoms, cycloalkyl of 3-8 carbon atoms, nitro, amino, —NR1R1a, —NR1COR1a, cycloalkylamino of 3-8 carbon atoms, morpholino, or OR8, or Z1and Z2may be taken together as a diene unit having the formula —CH═CR9—CR10═CR11—; or a pharmaceutically acceptable salt thereof, which are useful in treating metabolic disorders related to insulin resistance or hyperglycemia.