33839-11-1Relevant academic research and scientific papers
CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS
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Page/Page column 270, (2009/03/07)
The present invention relates to compounds of formula (I) for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases, including cathepsins B, K, C, F, H, L, O, S, W and X. Of particular interest are diseases associated with Cathepsin K.
INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME
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Page 127-128, (2008/06/13)
The invention relates to compounds of the formula (I) and to pharmaceutically acceptable salts, solvates, prodrugs and metabolites thereof, wherein W, Z, R1and R2, are as defined herein. The invention also relates to methods of treating Hepatitis C virus in mammals by administering the compounds of formula (I), and to pharmaceutical compositions for treating such disorders, which contain the compounds of formula (I). The invention also relates to methods of preparing the compounds of formula (I).
ACETYLATION, BROMINATION, AND NITRATION OF BENZOXAHETEROCYCLES AND SYNTHESIS OF β-AMINOKETONES FROM ACETYL DERIVATIVES
Daukshas, V. K.,Pyatrauskas, O. Yu.,Udrenaite, E. B.,Gaidyalis, P. G.,Gasperavichene, G. A.
, p. 838 - 841 (2007/10/02)
The method of competing reactions was used to establish the sequence of variation of the relative rates of acetylation, bromination, and nitration reactions of 2-methylcoumaran, chroman, 2,3,4,5-tetrahydrobenzo-1-oxepan, and 1-methoxy-2-ethylbenzene.The i
