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[2-(hydroxymethyl)-4,5-dimethoxy-phenyl]methanol, also known as syringaresinol, is a natural compound derived from the guaiacyl subunit of lignin. It is found in various plants, such as flaxseed, sesame seeds, avocado, and olive. Syringaresinol has been studied for its potential health benefits, including antioxidant and anti-inflammatory properties, as well as its potential use in the treatment of cancer, diabetes, and cardiovascular diseases. It also has anti-aging effects, making it a promising compound for cosmetic and skincare product development.

22943-99-3

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22943-99-3 Usage

Uses

Used in Pharmaceutical Applications:
Syringaresinol is used as a therapeutic agent for various health conditions due to its antioxidant, anti-inflammatory, and potential disease-treating properties. It is being investigated for its use in the treatment of cancer, diabetes, and cardiovascular diseases.
Used in Cosmetic and Skincare Applications:
Syringaresinol is used as an active ingredient in the development of cosmetic and skincare products, leveraging its anti-aging effects to improve skin health and appearance.
Used in Antioxidant Applications:
Syringaresinol is used as a natural antioxidant in the food and beverage industry, as well as in the pharmaceutical and cosmetic industries, to protect products from oxidative damage and extend their shelf life.
Used in Functional Food and Nutraceutical Applications:
Syringaresinol is used as a functional ingredient in the development of food and nutraceutical products, providing health benefits beyond basic nutrition, such as antioxidant and anti-inflammatory effects.
Used in Research and Development:
Syringaresinol is used as a compound of interest in scientific research, particularly in the fields of medicine, pharmacology, and wellness, to explore its potential applications and mechanisms of action in various health conditions and product development.

Check Digit Verification of cas no

The CAS Registry Mumber 22943-99-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,9,4 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 22943-99:
(7*2)+(6*2)+(5*9)+(4*4)+(3*3)+(2*9)+(1*9)=123
123 % 10 = 3
So 22943-99-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O4/c1-13-9-3-7(5-11)8(6-12)4-10(9)14-2/h3-4,11-12H,5-6H2,1-2H3

22943-99-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(hydroxymethyl)-4,5-dimethoxyphenyl]methanol

1.2 Other means of identification

Product number -
Other names 4,5-dimethoxyphthalyl alcohol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22943-99-3 SDS

22943-99-3Relevant academic research and scientific papers

A Unified Catalytic Asymmetric (4+1) and (5+1) Annulation Strategy to Access Chiral Spirooxindole-Fused Oxacycles

Gao, Min,Gong, Xiangnan,Hu, Lin,Luo, Yanshu,Xia, Yuanzhi,Xu, Qianlan,Zhao, Yukun

supporting information, p. 19813 - 19820 (2021/08/03)

A unified catalytic asymmetric (N+1) (N=4, 5) annulation reaction of oxindoles with bifunctional peroxides has been achieved in the presence of a chiral phase-transfer catalyst (PTC). This general strategy utilizes peroxides as unique bielectrophilic four- or five-atom synthons to participate in the C?C and the subsequent umpolung C?O bond-forming reactions with one-carbon unit nucleophiles, thus providing a distinct method to access the valuable chiral spirooxindole-tetrahydrofurans and -tetrahydropyrans with good yields and high enantioselectivities under mild conditions. DFT calculations were performed to rationalize the origin of high enantioselectivity. The gram-scale syntheses and synthetic utility of the resultant products were also demonstrated.

Synthesis of 1,2-phenylenedimethanols by base-promoted reduction of isobenzofuran-1(3H)-ones with silane

Liu, Bin,Zhou, Xigeng

supporting information, p. 725 - 728 (2018/12/11)

An efficient method for preparation of substituted 1,2-phenylenedimethanols and aliphatic 1,4-diols that are valuable intermediates in organic synthesis, has been developed by the base-promoted reduction of isobenzofuran-1(3H)-ones and γ-lactones with silane under mild conditions. Compared with traditional procedures using stoichiometric amounts of metal hydrides and alkyl reductants, the present method avoids the use of sensitive reagents and is operationally simple and a broad variety of functional groups are tolerated.

NOVEL BICYCLIC-COMPOUNDS FOR USE AS A MEDICAMENT, IN PARTICULAR FOR TREATMENT OF PARKINSON'S DISEASE

-

Page/Page column 18; 20, (2017/07/06)

The invention relates to novel small molecule compounds having a basic structure as depicted by formula (A), where in particular exemplary embodiments R1 is -OH, R2 is -NO2 and R3 is H, R4 and R5

Identification of Potential Off-target Toxicity Liabilities of Catechol-O-methyltransferase Inhibitors by Differential Competition Capture Compound Mass Spectrometry

Von Kleist, Lisa,Michaelis, Simon,Bartho, Kathrin,Graebner, Olivia,Schlief, Marén,Dreger, Mathias,Schrey, Anna K.,Sefkow, Michael,Kroll, Friedrich,Koester, Hubert,Luo, Yan

, p. 4664 - 4675 (2016/06/13)

Structurally related inhibitors of a shared therapeutic target may differ regarding potential toxicity issues that are caused by different off-target bindings. We devised a differential competition capture compound mass spectrometry (dCCMS) strategy to ef

Exploring O-stannyl ketyl and acyl radical cyclizations for the synthesis of γ-lactone-fused benzopyrans and benzofurans

Santoso, Helen,Casana, Myriam I.,Donner, Christopher D.

supporting information, p. 171 - 176 (2014/01/06)

The synthesis of a series of γ-lactone-fused benzopyrans and benzofurans, analogues of the pyranonaphthoquinone antibiotics, is reported. Preparation of the heterocycles was achieved by either O-stannyl ketyl or acyl radical cyclization of benzaldehyde pr

A practical 'one-pot' synthesis of ethyl isoquinoline-3-carboxylate by domino reactions: A potential entry to constrained nonproteogenic amino acid derivatives

Ameur Meziane, Mohamed A?t,Royer, Sylvain,Bazureau, Jean Pierre

, p. 1017 - 1020 (2007/10/03)

Two simple and efficient 'one-pot' preparations of isoquinoline-3-carboxylates by domino reactions using phthalaldehydes and imidate (route A) or diethyl aminomalonate (route B) are described. The third route involves the use of ethyl glycinate, aminoacet

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