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22952-20-1

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22952-20-1 Usage

General Description

1,2-Benzisothiazol-3(2H)-one, 5-nitro, 1,1-dioxide is a chemical compound with a nitro group and a dioxide group attached to a benzene ring. It is commonly used as a biocidal and antimicrobial agent in various industrial and consumer products, such as disinfectants and preservatives. 1,2-BENZISOTHIAZOL-3(2H)-ONE, 5-NITRO, 1,1-DIOXIDE has been found to have strong antibacterial and antifungal properties, making it effective in inhibiting the growth of microorganisms and preventing bacterial and fungal contamination. However, it is important to handle this chemical with care, as it can be harmful if ingested or if it comes into contact with the skin or eyes.

Check Digit Verification of cas no

The CAS Registry Mumber 22952-20-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,9,5 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22952-20:
(7*2)+(6*2)+(5*9)+(4*5)+(3*2)+(2*2)+(1*0)=101
101 % 10 = 1
So 22952-20-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4N2O5S/c10-7-5-3-4(9(11)12)1-2-6(5)15(13,14)8-7/h1-3H,(H,8,10)

22952-20-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-nitro-1,1-dioxo-1,2-benzothiazol-3-one

1.2 Other means of identification

Product number -
Other names 5-nitro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22952-20-1 SDS

22952-20-1Relevant articles and documents

Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors

Elsayed, Mohamed S.A.,El-Araby, Moustafa E.,Serya, Rabah A.T.,El-Khatib, Ahmed H.,Linscheid, Michael W.,Abouzid, Khaled A.M.

, p. 122 - 131 (2013/04/23)

This study is concerned with the implementation of structure-based techniques for the design of new heterocyclic compounds based on pseudosaccharine scaffold with protein kinase inhibition activity. This nucleus was exploited based on the well-known quinazoline core and its interactions with several protein kinases. Two series of compounds employing this new scaffold were synthesized and evaluated at enzymatic and cellular levels. Compound 9b displayed broad spectrum antiproliferative activity on NCI 60-cell lines panel with mean GI50 of 5.4 μM. Investigation of the molecular mechanism showed probable inhibitory activity against Src kinase.

Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists

Nerenberg, Jennie B.,Erb, Jill M.,Thompson, Wayne J.,Lee, Hee-Yoon,Guare, James P.,Munson, Peter M.,Bergman, Jeffrey M.,Huff, Joel R.,Broten, Theodore P.,Chang, Raymond S. L.,Chen, Tsing B.,O'Malley, Stacey,Schorn, Terry W.,Scott, Ann L.

, p. 2467 - 2472 (2007/10/03)

Benign prostatic hyperplasia can be managed pharmacologically with α-1 adrenergic receptor antagonists. Agents that demonstrate selectivity for the α-la receptor subtype may offer advantages in clinical applications with respect to hypotensive side effect

PREPARATION OF 5-NITROBENZOISOTHIAZOLONE AND ITS N-DERIVATIVES.

PONCI,BARUFFINI,CROCI,GIALDI

, p. 732 - 749 (2007/10/08)

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