22952-20-1

Usage

Uses

Used in Disinfectants:
1,2-Benzisothiazol-3(2H)-one, 5-nitro, 1,1-dioxide is used as a biocidal agent in disinfectants for its ability to effectively inhibit the growth of microorganisms, preventing bacterial and fungal contamination in various settings.
Used in Preservatives:
In the preservation industry, 1,2-Benzisothiazol-3(2H)-one, 5-nitro, 1,1-dioxide serves as an antimicrobial preservative, ensuring the longevity and safety of products by preventing spoilage and contamination caused by microbial growth.
Used in Industrial Applications:
1,2-Benzisothiazol-3(2H)-one, 5-nitro, 1,1-dioxide is utilized in various industrial applications as a biocidal agent to maintain cleanliness and prevent microbial contamination in manufacturing processes and equipment.
Used in Consumer Products:
This chemical compound is also found in consumer products, such as household cleaners and personal care items, where it acts as an antimicrobial agent to ensure cleanliness and prevent the spread of bacteria and fungi.
It is crucial to handle 1,2-Benzisothiazol-3(2H)-one, 5-nitro, 1,1-dioxide with care due to its potential harmful effects if ingested or if it comes into contact with the skin or eyes. Proper safety measures should be taken during its use to minimize any risks associated with exposure.

InChI:InChI=1/C7H4N2O5S/c10-7-5-3-4(9(11)12)1-2-6(5)15(13,14)8-7/h1-3H,(H,8,10)

Upstream product

• 62574-70-3 2-chlorosulfonyl-5-nitro-benzoyl chloride 
• 22952-19-8 2-methyl-4-nitrobenzenesulfonamide 
• 4337-52-4 5-nitro-1,2-benzisothiazol-3(2H)-one 
• 3816-62-4 5-nitroanthranilic acid methyl ester 
• 4693-02-1 6-nitroisatoic anhydride 
• 92906-21-3 2,2'-dithiobis-5-nitrobenzamide 
• 92030-46-1 5,5'-dinitro-2,2'-disulfanediyl-bis-benzoyl chloride 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 21320-90-1 5-nitro-2-toluenesulfonyl chloride 
• 1039020-81-9 2-methoxycarbonyl-4-nitrobenzenesulfonyl chloride 

Downstream Products

• 22094-61-7 5-aminobenzo[d]isothiazol-3(2H)-one 1,1-dioxide 
• 1428132-89-1 3-[(3-bromophenyl)amino]-5-nitrobenzo[d]isothiazole 1,1-dioxide 
• 1428132-90-4 3-[(4-chlorophenyl)amino]-5-nitrobenzo[d]isothiazole 1,1-dioxide 
• 1428132-91-5 3-[(2,4-dichlorophenyl)amino]-5-nitrobenzo[d]isothiazole 1,1-dioxide 
• 1428132-96-0 C₁₈H₁₇N₃O₅S 
• 1428132-97-1 C₁₇H₁₄BrN₃O₅S 
• 1428132-98-2 C₂₁H₂₀ClN₃O₆S 
• 1428132-99-3 C₂₁H₂₀BrN₃O₆S 
• 1428133-00-9 C₂₀H₁₄Cl₂N₄O₃S 
• 1428133-01-0 C₂₀H₁₃Cl₃N₄O₃S 
• 1428132-92-6 C₁₄H₁₃N₃O₂S 
• 1428132-93-7 C₁₃H₁₀BrN₃O₂S 
• 1428132-94-8 C₁₃H₁₀ClN₃O₂S 
• 1428132-88-0 5-nitro-3-(p-tolylamino)benzo[d]isothiazole 1,1-dioxide 

Relevant academic research and scientific papers

Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors

This study is concerned with the implementation of structure-based techniques for the design of new heterocyclic compounds based on pseudosaccharine scaffold with protein kinase inhibition activity. This nucleus was exploited based on the well-known quinazoline core and its interactions with several protein kinases. Two series of compounds employing this new scaffold were synthesized and evaluated at enzymatic and cellular levels. Compound 9b displayed broad spectrum antiproliferative activity on NCI 60-cell lines panel with mean GI50 of 5.4 μM. Investigation of the molecular mechanism showed probable inhibitory activity against Src kinase.

HYDRAZONE DERIVATIVE

A hydrazone derivative of formula [I]: wherein Ring A is aryl or heteroaryl, Ring T is heteroaryl or heterocycle, R1 and R2 are independently hydrogen atom, halogen atom, cycloalkylsulfonyl, etc., R3 and R4 comb

Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists

Benign prostatic hyperplasia can be managed pharmacologically with α-1 adrenergic receptor antagonists. Agents that demonstrate selectivity for the α-la receptor subtype may offer advantages in clinical applications with respect to hypotensive side effect