22952-80-3 Usage
Uses
Used in Pharmaceutical Industry:
Codeine 6-Methanesulfonate is used as a weak narcotic analgesic for the treatment of mild to moderate pain. Its conversion to morphine is believed to contribute to its pain-relieving effects.
Additionally, Codeine 6-Methanesulfonate is used as a potent antitussive agent to suppress coughing. This application is particularly useful in the treatment of conditions that cause excessive coughing, such as colds, bronchitis, and other respiratory illnesses.
Used in Research and Development:
Due to its chemical properties and pharmacological effects, Codeine 6-Methanesulfonate is also utilized in research and development for the study of pain management and cough suppression mechanisms. This helps in the development of new drugs and therapies for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 22952-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,9,5 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22952-80:
(7*2)+(6*2)+(5*9)+(4*5)+(3*2)+(2*8)+(1*0)=113
113 % 10 = 3
So 22952-80-3 is a valid CAS Registry Number.
22952-80-3Relevant academic research and scientific papers
A facile and improved synthesis of desomorphine and its deuterium-labeled analogue
Srimurugan, Sankareswaran,Su, Chi-Ju,Shu, Hun-Chi,Murugan, Kaliyappan,Chen, Chinpiao
scheme or table, p. 171 - 174 (2012/07/14)
This work describes a convenient and improved process for the synthesis of desomorphine from codeine. The proposed method affords the highly pure opiate without the aid of chromatographic purification, and provides a simple route for the synthesis of [2H3] deuterium-labeled desomorphine.
Conversions of tosyl and mesyl derivatives of the morphine group, XX. Synthesis of mesyl esters
Makleit,Berenyi,Bognar,Elek
, p. 161 - 163 (2007/10/10)
A simple and convenient method had been developed for the preparation of dihydro derivatives of morphine alkaloids. In this was, 3-O-ethyldihydromorphine was obtained in crystalline form. This compound is described in the literature as an oily product. Several 6-O-mesyl derivatives have been synthesized in good yields also on a larger scale from the dihydro compounds by the use of Crossland's method.
