229954-82-9

Upstream product

• 100-39-0 benzyl bromide 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 229954-81-8 3-azidopropyl (β-O-D-galactopyranosyl)-(1→4)-O-β-D-glucopyranoside 

Downstream Products

• 229954-83-0 3-azidopropyl 6-O-benzoyl-2,3-di-O-benzyl-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 229954-85-2 3-azidopropyl 2,6-di-O-benzyl-α-D-galactopyranosyl-(1->4)-6-O-benzoyl-2,3-di-O-benzyl-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 229954-84-1 3-azidopropyl 2,6-di-O-benzyl-3,4-di-O-isopropylidene-α-D-galactopyranosyl-(1->4)-6-O-benzoyl-2,3-di-O-benzyl-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 
• 646058-15-3 3-azidopropyl (2,3,6-O-tri-O-benzyl-β-D-galactopyranosyl)-(1→4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside 

Relevant academic research and scientific papers

Carbohydrate-lipid constructs and their use in preventing or treating viral infection

The invention relates to selected carbohydrate-lipid constructs and their use as mimics of ligands for receptors expressed by virus. In particular, the invention relates to the use of selected carbohydrate-lipid constructs in methods of inhibiting virus infection and/or promoting clearance of virus from infected subjects. Carbohydrate-lipid constructs selected for use in these methods where the virus is Human Immunodeficiency Virus (HIV) are provided.

Synthesis and NMR assignments of galactosylgloboside and its β-d-GalNAc-(1→4)-α-D-Gal-linked positional isomer in a conjugatable form

Two pentasaccharides suitable for conjugation, namely 3-aminopropyl glactosylgloboside and its β-D-GalNAc-(1→4)-α-D-Gal-linked positional isomer, were synthesized from 3(III),4(III)-di-O-unprotected globotrioside and the trichloroacetimidate of β-D-Gal-(1→3)-β-D-GalNPhth derivative. Glycosylation at both positions led to the formation of β-D-GalNPhth-(1→4)-α-D-Gal and β-D-GalNPhth-(1→3)-α-D-Gal-linked products in a ratio of 1:1 without selectivity. Complete NMR spectral assignments are also described. Copyright (C) 1999 Elsevier Science Ltd.