230-46-6

Basic information

• Product Name: 1,7-Phenanthroline
• Synonyms: AKOS 90061;1,7-PHENANTHROLINE;PHENANTHROLINE;M-PHENANTHROLINE;1,5-Diazaphenanthrene;4,10-Phenanthroline;NSC 35679;Pyrido[2,3-f]quinoline
• CAS NO: 230-46-6
• Molecular Formula: C₁₂H₈N₂
• Molecular Weight: 180.2053
• EINECS: 205-936-5
• Product Categories: Heterocyclic Building Blocks;N-Containing;Others
• Mol File: 230-46-6.mol

Chemical Properties

• Melting Point: 79-81℃
• Boiling Point: 365.1 °C at 760 mmHg
• Flash Point: 164.8 °C
• Appearance: /
• Density: 1.25 g/cm³
• Vapor Pressure: 3.38E-05mmHg at 25°C
• Refractive Index: 1.74
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: pK1:4.30(+1) (25°C)
• Water Solubility: It is soluble in water, ethanol, ether and benzene.
• CAS DataBase Reference: 1,7-Phenanthroline(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-Phenanthroline(230-46-6)
• EPA Substance Registry System: 1,7-Phenanthroline(230-46-6)

Safety Data

• Hazard Codes: Xn,N,T
• Statements: 22-41-50/53-25
• Safety Statements: 26-36/39-61-60-45-39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: SF8290000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 230-46-6(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
1,7-Phenanthroline is used as a chemical intermediate for the production of [1,7]phenanthroline-8-carbonitrile with hydrocyanic acid and potassium salt at a specific temperature. This synthesis is crucial for creating compounds with various applications in different industries.
Used in Plant Growth Inhibition:
1,7-Phenanthroline is used as a growth inhibitor in the agricultural industry to control the germination and growth of plants. Its inhibitory properties can be beneficial in managing plant growth and development, as well as in controlling weed populations.
Used in Chemical Research:
1,7-Phenanthroline serves as an important compound in chemical research, particularly in the study of supramolecular assemblies. Its interaction with other molecules, such as 1,2,4,5-benzenetetracarboxylic acid, has been investigated to understand its potential applications in various fields.

InChI:InChI=1/C12H8N2/c1-3-9-5-6-11-10(4-2-7-13-11)12(9)14-8-1/h1-8H

Upstream product

• 611-34-7 5-Aminoquinoline 
• 56-81-5 glycerol 
• 108-45-2 m-phenylenediamine 
• 76795-62-5 7-ethoxycarbonyl-7,8-dihydro-1,7-phenanthroline-8-carbonitrile 
• 7647-01-0 hydrogenchloride 
• 613-51-4 7-nitroquinoline 
• 99-09-2 3-nitro-aniline 

Downstream Products

• 89-00-9 Pyridine-2,3-dicarboxylic acid 

Related news

In vivo mutagenicity of benzo[f]quinoline, benzo[h]quinoline, and 1,7-Phenanthroline (cas 230-46-6) using the lacZ transgenic mice09/30/2019

Phenanthrene, a simplest angular polycyclic aromatic hydrocarbon with a bay-region in its molecule, is reported to be non-mutagenic, although most angular (non-linear) polycyclic aromatic hydrocarbons, such as benzo[a]pyrene and chrysene, are known to show genotoxicity after metabolic transforma...detailed

Barbituric acid in the synthesis of fused 1,7-Phenanthroline (cas 230-46-6) derivatives09/29/2019

New 7-aryl(hetaryl)-7,8,9,10,11,12-hexahydropyrimido[5,4-b][1,7]phenanthroline-9,11-diones have been synthesized by three-component condensation of barbituric acid with quinolin-5-amine and aromatic or heteroaromatic aldehydes.detailed

Aldehydes of furan series in the synthesis of 1,7-Phenanthroline (cas 230-46-6) derivatives09/28/2019

By condensation of quinolin-5-amine with 5-arylfuran-2-carbaldehydes and cyclohexane-1,3-dione or dimedone new compounds were synthesized, 10,10-dimethyl-7-(5-arylfuran-2-yl)-9,10,11,12-tetrahydrobenzo[b][1,7]phenanthrolin-8(7H)-ones unsubstituted in the position 10.detailed

Relevant articles and documents

Quinoline and phenanthroline preparation starting from glycerol via improved microwave-assisted modified Skraup reaction

An efficient "green" modified Skraup reaction in neat water was developed using inexpensive, abundant and environmentally-friendly glycerol under microwave irradiation conditions. Starting from aniline derivatives, various quinolines were obtained in 10-66% yields. The use of nitroaniline led to the corresponding phenanthrolines in 15-52% yields, respectively. This journal is the Partner Organisations 2014.

Heteroannulation of 3-Bis(methylthio)acrolein with Aromatic Amines - A Convenient Highly Regioselective Synthesis of 2-(Methylthio)quinolines and their Benzo/Hetero Fused Analogs: A Modified Skraup Quinoline Synthesis

A simple and efficient synthesis of 2-(methylthio)quinolines and their condensed analogs has been developed through acid-induced cyclocondensation of their respective anilines or aromatic diamines with 3-bis(methylthio)acrolein. The 2-(methylthio) functionality in these quinolines could be either dethiomethylated or replaced by various nitrogen and carbon nucleophiles to afford 2-substituted quinolines.

Photodynamic herbicides

Herbicidal compositions comprising one or more compounds selected from the group consisting of δ-aminolevulinic acid, inducers of δ-aminolevulinic acid, enhancers of δ-aminolevulinic acid conversion to photodynamic tetrapyrroles, and inhibitors of conversion of divinyl tetrapyrroles to monovinyl tetrapyrroles; and methods of making and using same.

Some Reactions of N-Alkoxycarbonyl Reissert Compounds with Heterocumulenes: Formation of the Imidazoisoquinoline and Imidazophthalazine Systems and Related Chemistry

Chloroformate derived Reissert compounds of isoquinoline and of phenanthridine on treatment with base undergo cyclisation with isothiocyanates to give in good yields corresponding imidazoisoquinoline and imidazophenanthroline derivatives.Phthalazine Reissert compound analogues give open chain adducts under the same conditions which can be cyclised to derivatives of the novel imidazophthalazine system by heating in the presence of molecular sieves.When carbon disulphide is the heterocumulene cyclisation is not observed but open chain dithio-ester derivatives can be isolated on alkylation of the intermediate sodium salts.