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6β-Fluor-9β,10α-pregn-4-en-3,20-dion is a synthetic steroid compound that belongs to the class of pregnanes. It is characterized by the presence of a fluorine atom at the 6β position and a double bond between the 9β and 10α carbons. This molecule features a 4-en structure, indicating a carbon-carbon double bond at the 4 position, and a 3,20-dione functional group, which consists of two carbonyl groups (C=O) at the 3 and 20 positions. The compound is derived from the parent steroid structure, pregnane, and is known for its potential applications in pharmaceutical research, particularly in the development of drugs targeting the endocrine system. Due to its unique structure, it may exhibit distinct biological activities compared to other pregnane derivatives.

2300-02-9

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2300-02-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2300-02-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,0 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2300-02:
(6*2)+(5*3)+(4*0)+(3*0)+(2*0)+(1*2)=29
29 % 10 = 9
So 2300-02-9 is a valid CAS Registry Number.

2300-02-9Relevant articles and documents

Kinetics of Electrophilic Fluorination of Steroids and Epimerisation of Fluorosteroids

Rozatian, Neshat,Harsanyi, Antal,Murray, Ben J.,Hampton, Alexander S.,Chin, Emily J.,Cook, Alexander S.,Hodgson, David R. W.,Sandford, Graham

, p. 12027 - 12035 (2020)

Fluorinated steroids, which are synthesised by electrophilic fluorination, form a significant proportion of marketed pharmaceuticals. To gain quantitative information on fluorination at the 6-position of steroids, kinetics studies were conducted on enol ester derivatives of progesterone, testosterone, cholestenone and hydrocortisone with a series of electrophilic N?F reagents. The stereoselectivities of fluorination reactions of progesterone enol acetate and the kinetic effects of additives, including methanol and water, were investigated. The kinetics of epimerisation of 6β-fluoroprogesterone to the more pharmacologically active 6α-fluoroprogesterone isomer in HCl/acetic acid solutions are detailed.

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