23002-14-4

Upstream product

• 1220282-36-9 N-(2-iodobenzyl)-4-methylbenzenamine 
• 1428264-89-4 2-isocyano-5-methyl-1,1'-biphenyl 
• 5720-07-0 4-methoxyphenylboronic acid 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 5467-74-3 4-Bromophenylboronic acid 
• 1679-18-1 4-Chlorophenylboronic acid 
• 16419-60-6 2-Methylphenylboronic acid 
• 98-80-6 phenylboronic acid 
• 583-68-6 2-bromo-p-toluidine 
• 42308-28-1 2-amino-5-methylbiphenyl 
• 1428264-96-3 C₁₄H₁₃NO 
• 4441-56-9 cyclohexylboronic acid 
• 110-82-7 cyclohexane 

Downstream Products

• 308821-51-4 (S,S,S)-1-(2'-methylphenanthridinyl)-4,7,10-tris[1-(1-phenyl)ethylcarbamoylmethyl]-1,4,7,10-tetraazacyclododecane 
• 41001-67-6 Phenanthridin-2-carbonsaeure 

Relevant academic research and scientific papers

A free radical cascade cyclization of isocyanides with simple alkanes and alcohols

A copper-catalyzed free-radical cascade cyclization of isocyanides with simple alkanes and alcohols was developed, which allowed convenient access to various alkyl-substituted phenanthridines.

Modular synthesis of phenanthridine derivatives by oxidative cyclization of 2-isocyanobiphenyls with organoboron reagents

Where HAS you been? A manganese-mediated annulation of 2-isocyanobiaryls with organoboronic acids is developed for the synthesis of a broad range of phenanthridine derivatives (see scheme). Mechanistic studies indicate that the reaction proceeds by the intramolecular homolytic aromatic substitution (HAS) of an imidoyl radical intermediate. Copyright

Electron-transfer-mediated synthesis of phenanthridines by intramolecular arylation of anions from n-(ortho-Halobenzyl)arylamines: regiochemical and mechanistic analysis

The synthesis of a series of substituted phenanthridines by photostimulated C-C cyclization of anions from N-(orrAo-halobenzyl)arylamines has been found to proceed in very good to excellent yields (79-95%) in liquid ammonia and in DMSO. The N-(ortho-halobenzyl)arylamines are obtained in good to very good isolated yields (44-85%) by nucleophilic substitution of orthohalobenzylchlorides with different arylamines. The reaction of the anions of a diverse set N-(orthohalobenzyl)arylamines was studied, and the methodology was extended to the synthesis of trispheridine, a natural product, in very good yield, In order to explain the regiochemical outcome of these reactions, a theoretical analysis was performed with DFT methods and the B3LYP functional.