23012-13-7

Usage

Uses

Used in Pharmaceutical Industry:
Oxazole-4-carboxylic acid is used as a key intermediate in the synthesis of various heterocyclic compounds, which are essential in the development of new drugs and therapeutic agents. Its unique structure and properties make it a valuable building block for creating novel molecules with potential applications in medicine.
Used in Cancer Treatment:
Oxazole-4-carboxylic acid is used as a STING agonist in the treatment of cancer. STING agonists are a class of compounds that activate the STING pathway, which plays a crucial role in the immune system's response to cancer cells. By stimulating this pathway, Oxazole-4-carboxylic acid-derived STING agonists can enhance the immune system's ability to recognize and eliminate cancer cells, offering a promising approach to cancer treatment.

InChI:InChI=1/C4H3NO3/c6-4(7)3-1-8-2-5-3/h1-2H,(H,6,7)

Upstream product

• 170487-38-4 methyl 4.-oxazolecarboxylate 
• 23012-14-8 oxazole-4-carboxylic acid ethyl ester 

Downstream Products

• 288-42-6 oxazol 
• 7164-98-9 1-phenylimidazole 
• 170486-48-3 N-methoxy-N-methyloxazole-4-carboxamide 
• 1361188-23-9 5-{4-[1-(5-oxazol-4-yl-[1,2,4]oxadiazol-3-yl)cyclobutyl]phenyl}pyrimidin-2-ylamine 
• 1610711-25-5 N-(3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9H-purin-6-yl]amino}cyclohexyl)-1,3-oxazole-4-carboxamide 
• 1263184-05-9 C₂₉H₃₁N₅O₄ 
• 1123581-56-5 N-{6-[3-({[4-(trifluoromethyl)phenyl]amino}carbonyl)phenoxy]-1,3-benzothiazol-2-yl}-1,3-oxazole-4-carboxamide 
• 1123581-34-9 N-[6-(5-([3-(1-cyano-1-methylethyl)benzoyl]amino}-2-methoxyphenoxy)-1,3-benzothiazol-2-yl]-1,3-oxazole-4-carboxamide 
• 1123580-91-5 N-[6-(3-{[3-(1-cyanocyclopropyl)benzoyl]amino}phenoxy)-1,3-benzothiazol-2-yl]-1,3-oxazole-4-carboxamide 
• 62348-20-3 oxazol-4-ylcarbonyl chloride 

Relevant academic research and scientific papers

ALKYNYL ALCOHOLS AS KINASE INHIBITORS

Selected compounds are effective for prophylaxis and treatment of inflammation and inflammatory disorders, such as NIK-mediated disorders. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, inflammation and the like.

AMINE-LINKED PYRIDYL AND PHENYL SUBSTITUTED PIPERAZINE-PIPERIDINES WITH CXCR3 ANTAGONIST ACTIVITY

The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers, racemates or prodrug of said compound, or pharmaceutically acceptable salts, solvates or esters of said compound, or of said prodrug, said compound having th

A practical synthesis of 1,3-oxazole

A short synthesis of oxazole (1,3-oxazole, 1) is described.