23019-62-7

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 1-benzyl-1,2,3,6-tetrahydropyridine-4-carboxylate is used as a synthetic intermediate for the creation of various pharmaceuticals. Its role in this industry is pivotal due to its potential to contribute to the development of new drugs that address a spectrum of medical conditions.
Used in Organic Chemistry:
In the realm of organic chemistry, Ethyl 1-benzyl-1,2,3,6-tetrahydropyridine-4-carboxylate serves as a key component in the synthesis of other organic compounds. Its structural features make it a versatile building block for creating complex organic molecules with specific applications in various fields.
It is imperative to handle Ethyl 1-benzyl-1,2,3,6-tetrahydropyridine-4-carboxylate with care, adhering to all safety precautions and regulatory guidelines to ensure the safe and effective use of this chemical compound in its respective applications.

InChI:InChI=1/C15H19NO2/c1-2-18-15(17)14-8-10-16(11-9-14)12-13-6-4-3-5-7-13/h3-8H,2,9-12H2,1H3

Upstream product

• 1570-45-2 isonicotinic acid ethylester 
• 100-39-0 benzyl bromide 
• 23019-61-6 1-benzyl-4-(ethoxycarbonyl)pyridin-1-ium bromide 

Relevant academic research and scientific papers

Metal-free reduction of unsaturated carbonyls, quinones, and pyridinium salts with tetrahydroxydiboron/water

A series of unsaturated carbonyls, quinones, and pyridinium salts have been effectively reduced to the corresponding saturated carbonyls, dihydroxybenzenes, and hydropyridines in moderate to high yields with tetrahydroxydiboron/water as a mild, convenient, and metal-free reduction system. Deuterium-labeling experiments have revealed this protocol to be an exclusive transfer hydrogenation process from water. This journal is

Efficient and chemoselective reduction of pyridines to tetrahydropyridines and piperidines via rhodium-catalyzed transfer hydrogenation

Promoted by iodide anion the rhodium complex dimer, [Cp RhCl 2]2, catalyzes efficiently the transfer hydrogenation of various quaternary pyridinium salts under mild conditions, affording not only piperidines but also 1,2,3,6-tetrahydropyridines in a highly chemoselective fashion, depending on the substitution pattern at the pyridinium ring. The reduction is conducted in azeotropic formic acid/triethylamine (HCOOH-Et 3N) mixture at 40 °C, with catalyst loadings as low as 0.005mol% being feasible. Copyright

New anti-MRSA and anti-VRE carbapenems: Synthesis and structure-activity relationships of 1β-metyl-2-(thiazol-2-ylthio)carbapenems

Discovery of novel antimicrobial agents effective against infections caused by drug-resistant pathogens is an important objective. In order to find a new parenteral carbapenem antibiotic, which has potent antibacterial activity especially against methicillin-resistant staphylococci, vancomycin-resistant enterococci and penicillin-resistant Streptococcus pneumoniae, a series of 1β-methylcarbapenems with thiazol-2-ylthio groups at the C-2 position have been synthesized. Structure-activity relationships were investigated which led to SM-197436 (27), SM-232721 (44) and SM-232724 (41), being selected for further evaluation.