230291-43-7

Basic information

• Product Name: 1H-Indole-2-carboxylic acid, 4-chloro-, Methyl ester
• Synonyms: 1H-Indole-2-carboxylic acid, 4-chloro-, Methyl ester
• CAS NO: 230291-43-7
• Molecular Formula: C10H8ClNO2
• Molecular Weight: 209.62902
• Mol File: 230291-43-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 146-147 °C
• Boiling Point: 365.5±22.0 °C(Predicted)
• Appearance: /
• Density: 1.381±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.07±0.30(Predicted)
• CAS DataBase Reference: 1H-Indole-2-carboxylic acid, 4-chloro-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxylic acid, 4-chloro-, Methyl ester(230291-43-7)
• EPA Substance Registry System: 1H-Indole-2-carboxylic acid, 4-chloro-, Methyl ester(230291-43-7)

Safety Data

• Hazardous Substances Data: 230291-43-7(Hazardous Substances Data)

Usage

General Description

1H-Indole-2-carboxylic acid, 4-chloro-, Methyl ester is a chemical compound with the molecular formula C10H8ClNO2. It is a derivative of indole, a heterocyclic aromatic compound, and is commonly used in the synthesis of pharmaceuticals and agrochemicals. 1H-Indole-2-carboxylic acid, 4-chloro-, Methyl ester is a methyl ester, which means it contains a methyl group attached to the carboxylic acid functional group. The presence of the 4-chloro substituent on the indole ring gives the compound its specific chemical properties and potential uses in various applications. As a methyl ester, it can be easily manipulated in organic synthesis reactions to produce a wide range of related compounds with diverse chemical properties.

Upstream product

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• 67-56-1 methanol 

Downstream Products

• 23967-44-4 4-chloro-1-methyl-1H-indole-2-carboxylic acid 

Relevant articles and documents

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

[Fe(F20TPP)Cl] catalyzed intramolecular C-N bond formation for alkaloid synthesis using aryl azides as nitrogen source

The syntheses of alkaloids including indoles, indolines, tetrahydroquinolines, dihydroquinazolinones and quinazolinones have been accomplished in moderate to excellent yields via [Fe(F20TPP)Cl] catalyzed intramolecular C-N bond formation using aryl azides as nitrogen source.

Intramolecular C-H amination reactions: Exploitation of the Rh 2(II)-catalyzed decomposition of azidoacrylates

Rhodium(II) perfluorobutyrate-mediated decomposition of vinyl azides provides a new, mild entry into Rh2(II) nitrenoid chemistry. This methodology allows rapid access to a variety of complex, functionalized N-heterocycles in two steps from commercially available starting materials. Copyright