2305-26-2Relevant academic research and scientific papers
Spontaneous formation and stabilization of radicals during the cocrystallization of alicyclic and peroxyalicyclic dicarboxylic acids
Starostin, Evgenii K.,Lalov, Andrei V.,Ignatenko, Anatolii V.,Nikishin, Gennady I.
, p. 123 - 125 (2008)
The cocrystallization of di(cis-2-carboxycyclohexylcarbonyl) peroxide and cyclohexane-1,2-dicarboxylic acid from aqueous solution affords stable 1-carboxycyclohexyl radicals, which were identified by EPR spectroscopy.
Production synthesis method of cis-1, 2, 3, 6-tetrahydrophthalimide
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Paragraph 0024-0026, (2020/08/06)
The invention provides a production synthesis method of cis-1, 2, 3, 6-tetrahydrophthalimide. The method comprises the following steps: S1, heating and melting solid 1, 2, 3, 6-tetrahydrophthalic anhydride, stirring, raising the temperature, stopping heating, adding urea at a specific constant speed, preserving heat for 3-5 minutes, then adding urea at the same constant speed again at 130-135 DEGC, preserving heat for 2-2.5 hours, and stopping reaction after the reaction is detected to be complete, and S2, heating and dissolving the product obtained in the step S1 with deionized water, cooling, standing to separate out crystals, carrying out suction filtration, washing with ice water, and drying to obtain white cis-1, 2, 3, 6-tetrahydrophthalimide. According to the method, urea is continuously added in batches at a specific temperature, so that the utilization rate of raw materials is effectively increased, side reactions are reduced, the product quality is improved, the conditions inthe synthesis process are mild and controllable, and environmental protection and actual industrial application are facilitated.
RECYCLABLE POLYMERS BASED ON RING-FUSED GAMMA-BUTYROLACTONES
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Page/Page column 34; 44; 48, (2020/02/23)
The invention discloses a class of new polymers, trans-ring-fused poly(4-hydroxybutyrate)s (RF-P4HB) that exhibit a unique set of properties, including robust thermal stability and mechanical strength, quantitative recyclability to the building block monomers via thermolysis and/or chemical catalysis, and convenient production from the chemical ring-opening polymerization under ambient temperature and pressure. Another unique property is the formation of crystalline stereocomplexed polymers with high melting temperature upon mixing the two enantiomeric RF-P4HB chains via stereocomplexing co-crystallization. This invention also provides the corresponding ring-fused lactone monomer structures that enable the synthesis of the RF-P4HB polymers, through trans-fusing of rings to the parent γ-butyrolactone ring. Furthermore, a polymerization or copolymerization process for the synthesis of RF-P4HB polymers and copolymers is disclosed.
Simple and efficient synthesis of new tricarboxylic acids bearing cyclohexane and norbornane fragments
Firstova,Kofanov,Krasovskaya,Danilova
, p. 867 - 869 (2017/09/29)
A synthesis new aryl alicyclic tricarboxylic acids bearing two carboxyl groups at either cyclohexane or norbornane fragment and one carboxyl group at the benzene ring was devel-oped. Tricarboxylic acids of this type are promising monomers for the synthesis of hetero-cyclic polymers.
Truncated borrelidin analogues: Synthesis by sequential cross metathesis/olefination for the southern fragment and biological evaluation
Gündemir-Durmaz, Tülay,Schmid, Fabian,El Baz, Yana,H?usser, Annette,Schneider, Carmen,Bilitewski, Ursula,Rauhut, Guntram,Garnier, Delphine,Baro, Angelika,Laschat, Sabine
supporting information, p. 8261 - 8269 (2016/09/09)
The construction of novel borrelidin analogues is reported in which the northern fragment is truncated to a simple hydroxyundecanecarboxylate and the original cyclopentanecarboxylic acid in the southern fragment is replaced with different six-membered rings. The required precursors were prepared by cross metathesis of the appropriate carbocycle-based homoallylic alcohol with crotonaldehyde followed by HWE olefination of the resulting enal with bromocyanophosphonate. The key aldehyde for intramolecular cross coupling was accessible by oxidation of the hydroxy group of the linked undecanecarboxylate unit. Grignard mediated macrocyclization finally yielded the borrelidin related products. The investigation is complemented by SAR studies and quantum-chemical calculations.
PROCESS FOR PREPARING BENZISOTHIAZOL-3-YL-PEPERAZIN-L-YL-METHYL-CYCLO HEXYL-METHANISOINDOL-1,3-DIONE AND ITS INTERMEDIATES
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Page/Page column 25; 26, (2013/08/28)
The present invention discloses process for preparing benzisothiazol-3-yl- piperazin-l-yl-methyl-cyclo hexyl-methanisoindol-l,3-dione and intermediates thereof.
Synthesis and structure of new trichloroplatinum π-complexes: Reactivity of nitrogen lone-pair versus C-C double bond π-electrons in ligands, effect of steric hindrance
Gay, Marina,Monta?a, ángel M.,Moreno, Virtudes,Font-Bardia, Mercè,Solans, Xavier
, p. 4856 - 4866 (2007/10/03)
Two trichloroplatinum π-complexes and a diammonium tetrachloroplatinate (II) salt have been unexpectedly isolated during the attempt to synthesize the corresponding cisplatinum square-planar complexes of tertiary cyclohexane 1,4-diamines. All three compounds have been physically and spectroscopically characterized, including X-ray diffraction analysis in two of the three compounds. The formation of the π-complexes instead of the diamino cis-platinum complexes could be explained as due to the steric hindrance exerted by methyl groups on the tertiary amines. So, the π-electrons of the CC double bond are more available than the electron lone pair of nitrogen atom from the amino groups. When the π-electrons of the CC from the molecule of ligand were made unavailable by transforming the cyclohexene subunit into a benzene aromatic ring, no cis-diamino dichloro platinum(II) complex nor trichloroplatinum-complexes were isolated but the corresponding tetrachloroplatinate(II) diammonium salt of the 1,4-diamino ligand.
Synthesis and structure of an unexpected platinum π complex formed from substituted 1,4-diamino ligands through an elimination process
Gay, Marina,Montana, Angel M.,Moreno, Virtudes,Font-Bardia, Merce,Solans, Xavier
, p. 2130 - 2134 (2007/10/03)
An unusual reactivity of cis-1,2-bis[(N,N-dimethylamino)methyl] cyclohexane with PtCl2 was observed, resulting in the formation of a platinum(II) π-olefin complex instead of the conventional square-planar cis PtII coordination complex with the diamino ligand. This behavior was interpreted on the basis of the steric hindrance of the dimethylamino groups whose electron lone pairs are barely accessible to a platinum atom, which can make it difficult for both dimethylamino groups to bind platinum at the same time. This complex has been physically and spectroscopically characterized and its structure has been confirmed by using X-ray diffraction analyses on single crystals.
Synthesis of diazacrown compounds with polyfunctional cyclohexane fragments
Shabanov,Mamedov,Mamedov
, p. 589 - 592 (2007/10/03)
A convenient synthetic method was developed for new diazacrown compounds that contained at polyether cavity polyfunctional cyclohexene or cyclohexane fragments of definite configuration. The synthetic procedure consists in fusion in toluene of equimolar quantities of anhydrides of 4-cyclohexene and 4,5-trans-dibromocyclohexane-cis-1,2-dicarboxylic acids with hydroxy-substituted diazacrown ether. The crown compounds synthesized under complexing conditions with AgBF4 undergo disproportionation yielding bis-crown compounds.
Improved synthesis of both enantiomers of trans-cyclohex-4-ene-1,2- dicarboxylic acid
Bernardi, Anna,Arosio, Daniela,Dellavecchia, Donatella,Micheli, Fabrizio
, p. 3403 - 3407 (2007/10/03)
A facile synthesis of both enantiomers of trans-cyclohex-4-ene-1,2- dicarboxylic acid on a multigram scale, that starts from inexpensive, commercially available compounds, is described.
