23056-46-4

Basic information

• Product Name: 2-BROMO-3-NITRO-5-METHYL PYRIDINE
• Synonyms: 2-BROMO-3-NITRO-5-METHYL PYRIDINE;2-Bromo-5-methyl-3-nitropyridine;2-BROMO-3-NITRO-5-PICOLINE;2-BROMO-3-NITRO-5-PICOLINE (2-BROMO-5-METHYL-3-NITROPYRIDINE);6-Bromo-5-nitro-3-picoline;2-Bromo-3-nitro-5-methyl pyridine ,98%;Pyridine,2-broMo-5-Methyl-3-nitro-
• CAS NO: 23056-46-4
• Molecular Formula: C₆H₅BrN₂O₂
• Molecular Weight: 217.0201
• Product Categories: Pyridine;Boronic Acid;Heterocycle-Pyridine series
• Mol File: 23056-46-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 276.699 °C at 760 mmHg
• Flash Point: 121.144 °C
• Appearance: /
• Density: 1.709 g/cm³
• Vapor Pressure: 0.00796mmHg at 25°C
• Refractive Index: 1.599
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.95±0.20(Predicted)
• CAS DataBase Reference: 2-BROMO-3-NITRO-5-METHYL PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-3-NITRO-5-METHYL PYRIDINE(23056-46-4)
• EPA Substance Registry System: 2-BROMO-3-NITRO-5-METHYL PYRIDINE(23056-46-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 23056-46-4(Hazardous Substances Data)

Usage

General Description

2-Bromo-3-nitro-5-methyl pyridine is a chemical compound with the molecular formula C6H5BrN2O2. It is a bromo-substituted pyridine derivative that contains a nitro group and a methyl group. 2-BROMO-3-NITRO-5-METHYL PYRIDINE is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has applications in the field of medicinal chemistry and drug discovery, where it is utilized as a key intermediate in the production of various bioactive molecules. Additionally, 2-bromo-3-nitro-5-methyl pyridine has been investigated for its potential as a reagent in organic synthesis and chemical research.

InChI:InChI=1/C6H5BrN2O2/c1-4-2-5(9(10)11)6(7)8-3-4/h2-3H,1H3

Upstream product

• 7464-14-4 2-hydroxy-5-methyl-3-nitropyridine 
• 7598-26-7 5-Methyl-3-nitro-2-aminopyridine 

Downstream Products

• 1089330-68-6 2-cyano-5-methyl-3-nitropyridine 
• 34552-14-2 3-amino-2-bromo-5-methylpyridine 

Relevant articles and documents

FUSED HETEROARYL PYRIDYL AND PHENYL BENZENESUFLONAMIDES AS CCR2 MODULATORS FOR THE TREAMENT OF INFLAMMATION

Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2- mediated diseases and as controls in assays for the identification of CCR2 antagonists. A compound of the formula (I) or a salt thereof: where: R1 and R2 are each independently hydrogen, halogen, C1-8alkyl, -CN. or C1-8 haloalkyl, provided that at least one of R11or R2 is other than hydrogen; each R3 is independently hydrogen; R4 is hydrogen; R5 is halogen or C1-8 alkyl; R6 is hydrogen; X1 is CR7, N or NO; X2 and X4 are N or NO; X3 is CR7; X6 and X7 are each independently selected from CR7, N, and NO; each R7 is independently selected from the group consisting of hydrogen, halogen, substituted or unsubstituted C2-8 alkyl, substituted or unsubstituted C2-8 alkeπyl, substituted or unsubstituted C2-8 alkynyl, -CN. =O, -NO2, -OR6, -OC(O)R8, -CO2R8, -C(O)R8, -C(O)NR0R8, -OC(O)NR9R8, -NR10C(O)R8, -NR10C(O)NR9R8, -NR9R8, -NR10CO2R8, -SR8, -S(O)R8, -S(O)2R8, -S(O)2NR9R8, -NR10S(O)2R8, substituted or unsubstituted C6-10 aryl, substituted or unsubstituted 5- to 10-membered heteroaryl and substituted or unsubstituted 3- to 10-membered heterocyclyl;