34552-14-2

Usage

Uses

Used in Pharmaceutical Industry:
3-AMINO-2-BROMO-5-PICOLINE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-AMINO-2-BROMO-5-PICOLINE serves as an intermediate in the production of agrochemicals, aiding in the creation of compounds that can protect crops and enhance agricultural productivity.
Used in Organic Chemistry Research:
3-AMINO-2-BROMO-5-PICOLINE is utilized as a building block and reagent in organic chemistry research, facilitating the exploration of new chemical reactions and the synthesis of novel organic compounds.
Safety Considerations:
Due to its potential harmful effects, 3-AMINO-2-BROMO-5-PICOLINE should be handled with care to avoid skin contact, eye contact, or ingestion, ensuring the safety of individuals working with this chemical in both laboratory and industrial environments.

InChI:InChI=1/C6H7BrN2/c1-4-2-5(8)6(7)9-3-4/h2-3H,8H2,1H3

Upstream product

• 3430-19-1 5-methylpyridin-3-amine 
• 23056-46-4 2-bromo-5-methyl-3-nitropyridine 

Relevant academic research and scientific papers

PYRROLIDINYL UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS

Compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where R1, R2, Ra, Rb, Rc, Rd, X, Ring B, and Ring C are as defined herein, and wherein Ring B moiety and the NH-C(=X)-NH moiety are in the trans configuration, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.

HETEROARYL SULFONAMIDES AND CCR2

Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.

Bromination of Pyridines. II. Bromination of Aminopicolines

The bromination of all ten possible aminopicolines 1-10 was investigated.In general, the major brominated product was that corresponding to electrophilic attack at the sites para or ortho to the amino group.