23062-42-2Relevant articles and documents
A novel and expeditious approach to thiophene-3-carboxylates
Fevig,Phillips,Lau
, p. 2493 - 2497 (2001)
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Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists
Nagashima, Shinya,Matsushima, Yuji,Hamaguchi, Hisao,Nagata, Hiroshi,Kontani, Toru,Moritomo, Ayako,Koshika, Tadatsura,Takeuchi, Makoto
, p. 3478 - 3487 (2014/06/23)
Herein, we describe the synthesis and pharmacological profiles of novel quinuclidinyl heteroarylcarbamate derivatives. Among them, the quinuclidin-4-yl thiazolylcarbamate derivative ASP9133 was identified as a promising long-acting muscarinic antagonist (LAMA) showing more selective inhibition of bronchoconstriction against salivation and more rapid onset of action in a rat model than tiotropium bromide.
COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM
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Page/Page column 113, (2009/07/17)
Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combinatio