230962-34-2Relevant academic research and scientific papers
A potent, selective inhibitor of matrix metalloproteinase-3 for the topical treatment of chronic dermal ulcers
Fray, M. Jonathan,Dickinson, Roger P.,Huggins, John P.,Occleston, Nicholas L.
, p. 3514 - 3525 (2007/10/03)
The pathology of chronic dermal ulcers is characterized by excessive proteolytic activity which degrades extracellular matrix (required for cell migration) and growth factors and their receptors. The overexpression of MMP-3 (stromelysin-1) and MMP-13 (col
Matrix metalloprotease inhibitors
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Example 37, (2012/04/23)
Compounds of formula (I): or pharmaceutically acceptable salts thereof, or solvates of either entity, wherein the substituents have the values described herein, are useful as matrix metalloprotease (MMP) inhibitors
