2310-87-4Relevant articles and documents
Simple method for cleavage of phosphonic acid diesters to monoesters
Holy, Antonin
, p. 381 - 385 (2007/10/03)
Phosphonic acid dialkyl or diaryl esters give, on treatment with alkali azide or alkali iodide in DMF at 100°C, quantitatively and specifically the corresponding monoesters. The reaction is applied in a series of acyclic nucleotide analogs for the preparation of PMEA monoesters and related compounds.