23120-58-3Relevant academic research and scientific papers
Transition-Metal-Free Highly Chemoselective and Stereoselective Reduction with Se/DMF/H2O System
Li, Hong-Chen,An, Cui,Wu, Ge,Li, Guo-Xing,Huang, Xiao-Bo,Gao, Wen-Xia,Ding, Jin-Chang,Zhou, Yun-Bing,Liu, Miao-Chang,Wu, Hua-Yue
supporting information, p. 5573 - 5577 (2018/09/12)
A novel metal-free reduction system, in which H2Se (or HSe-) produced in situ from Se/DMF/H2O acts as the active reducing species, has been developed. By using water as an inexpensive, safe, and environmentally friendly surrogate as the hydrogen donor, this new reduction system incorporating Se/DMF/H2O displayed high selectivity and good activity in the reduction of α,β-unsaturated ketones and alkynes. Therefore, this reduction system has great potential to be a general and practical reduction methodology in organic transformation.
Compound capable of effectively inhibiting or killing multi-drug resistant bacteria and preparation method and application of compound
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Paragraph 0147; 0149; 0437; 0438; 0439; 0440; 0441-0451, (2017/06/02)
The invention discloses a compound capable of effectively inhibiting or killing bacterial microorganisms. The compound has a structural general formula shown as the formula I (please see the formula in the description). Pharmacodynamic experiments prove that the compound can effectively inhibit or kill the broad-spectrum and multi-drug resistant staphylococcus aureus, streptococcus pneumoniae and staphylococcus aureus and is expected to be developed into a novel effective antibacterial drug with new targets.
Synthesis, characterization, and cytotoxic activities of heterocyclic chalcones containing furan, and crystal structure of 1-(4-iodophenyl)-3-(5-methylfuran-2-yl)prop-2-en-1-one
Mokhtar, Zakiah,Jamalis, Joazaizulfazli,Bohari, Siti Pauliena Mohd,Rosli, Mohd Mustaqim,Fun, Hoong-Kun
, p. 119 - 131 (2016/07/21)
A series of heterocyclic chalcone (3a–e, 5, 7) were synthesized and characterized by Infrared, 1H and 13C nuclear magnetic resonance, and mass spectra. Crystal structure of 1-(4-iodophenyl)-3-(5-methylfuran-2-yl)prop-2-en-1-one was d
