23128-51-0

Basic information

• Product Name: 3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide
• Synonyms: N-[3-[bis[2-(acetyloxy)ethyl]amino]-4-methoxyphenyl]-Acetamide;2-(N,N-DIACETOXYETHYL)-AMINO-4-ACETAMINOANISOLE;3-DIACETOXYETHYLAMINO-4-METHOXY ACETANILIDE;3-(N,N-DIACETOXYETHYL)AMINO-4-METHOXY ACETANILIDE;2,2'-[[5-acetamido-2-methoxyphenyl]imino]diethyl diacetate;acetamide,N-[3-[bis[2-(acetyloxy)ethyl]amino]-4-methoxyphenyl]-;3-(N,N-Diacetoxylethyl)amino-4-methoxylacetanilide;3''-[N,N-Bis-(2-acetoxyethyl)-amino]-4''-methoxyacetanilide
• CAS NO: 23128-51-0
• Molecular Formula: C₁₇H₂₄N₂O₆
• Molecular Weight: 352.38
• EINECS: 245-441-1
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 23128-51-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 526.783 °C at 760 mmHg
• Flash Point: 272.389 °C
• Appearance: /
• Density: 1.213 g/cm³
• Vapor Pressure: 3.46E-11mmHg at 25°C
• Refractive Index: 1.552
• PKA: 14.29±0.70(Predicted)
• CAS DataBase Reference: 3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide(23128-51-0)
• EPA Substance Registry System: 3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide(23128-51-0)

Safety Data

• Hazardous Substances Data: 23128-51-0(Hazardous Substances Data)

Usage

Description

3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide, also known as acetoxydihydroxypropylaminopara-methoxyacetanilide, is an organic compound within the acetanilide class. It is synthesized from acetoxyethylamine and 4-methoxyacetanilide and features an acetanilide moiety with an amine and an acetoxyethyl group at the para position of the phenyl ring. 3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide is recognized for its potential pharmaceutical applications, owing to its structural resemblance to established analgesic and anti-inflammatory drugs, and is a valuable reagent in organic chemistry and pharmaceutical research.

Uses

Used in Pharmaceutical Research:
3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide is used as a research compound for its potential analgesic and anti-inflammatory properties due to its structural similarities with known drugs in these categories.
Used in Organic Chemistry:
In the field of organic chemistry, 3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide serves as a reagent, facilitating various chemical reactions and synthesis processes.
Used in Drug Development:
3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide is utilized in drug development studies, given its specific properties that make it a promising candidate for the creation of new pharmaceuticals, particularly in the areas of pain management and inflammation reduction.
Used in Chemical Synthesis:
3-(N,N-Diacetoxyethyl)amino-4-methoxyacetanilide is employed in chemical synthesis for the production of other organic compounds, leveraging its unique structural features to form new molecules with potential applications in various industries.

InChI:InChI=1/C17H24N2O6/c1-12(20)18-15-5-6-17(23-4)16(11-15)19(7-9-24-13(2)21)8-10-25-14(3)22/h5-6,11H,7-10H2,1-4H3,(H,18,20)

Upstream product

• 108-24-7 acetic anhydride 
• 24530-67-4 N-{3-[bis(2-hydroxyethyl)amino]-4-methoxyphenyl}acetamide 
• 64-19-7 acetic acid 
• 6375-47-9 3-amino-4-methoxyacetanilide 
• 108-45-2 m-phenylenediamine 

Downstream Products

• 76486-27-6 Acetic acid 2-{(2-acetoxy-ethyl)-[5-acetylamino-4-(2-cyano-4-nitro-phenylazo)-2-methoxy-phenyl]-amino}-ethyl ester 
• 76486-17-4 Acetic acid 2-{(2-acetoxy-ethyl)-[5-acetylamino-4-(2-cyano-4-nitro-naphthalen-1-ylazo)-2-methoxy-phenyl]-amino}-ethyl ester 
• 3618-73-3 2,2'-({5-acetamido-4-[(2-chloro-4,6-dinitrophenyl)azo]-2-methoxyphenyl}imino)diethyl diacetate 
• 3618-66-4 C₂₃H₂₆N₆O₁₀ 
• 88167-23-1 Acetic acid 2-{(2-acetoxy-ethyl)-[5-acetylamino-4-(2-cyano-4,6-dinitro-phenylazo)-2-methoxy-phenyl]-amino}-ethyl ester 
• 105674-53-1 4-{2-Acetylamino-4-[bis-(2-acetoxy-ethyl)-amino]-5-methoxy-phenylazo}-3,5-dicyano-benzoic acid ethyl ester 
• 107829-00-5 Acetic acid 2-{(2-acetoxy-ethyl)-[5-acetylamino-4-(2,6-dicyano-4-nitro-phenylazo)-2-methoxy-phenyl]-amino}-ethyl ester 
• 3618-72-2 Disperse Blue 79 
• 87260-48-8 Acetic acid 2-{(2-acetoxy-ethyl)-[5-acetylamino-4-(2-bromo-6-cyano-4-nitro-phenylazo)-2-methoxy-phenyl]-amino}-ethyl ester 

Relevant articles and documents

Preparation method of 2-methoxy-5-acetamido-N, N-diacetoxyethyl aniline

The invention provides a preparation method of 2-methoxy-5-acetamido-N, N-diacetoxyethyl aniline. The method comprises the following steps: (1) carrying out hydroxylation reaction on o-methoxy m-acetamido aniline and ethylene oxide to obtain a hydroxylate 2-methoxy-5-acetamido-N, N-dihydroxyethyl aniline; and step 2), carrying out an esterification reaction on the hydroxylate 2-methoxy-5-acetamido-N, N-dihydroxyethyl aniline and acetic anhydride and/or acetic acid, so as to obtain an esterified compound. The 2-methoxy-5-acetamido-N, N-diacetoxyethyl aniline prepared by the method disclosed by the invention is low in cost and simple in steps, and the obtained product is high in yield, high in purity and more suitable for workshop production.