231280-23-2

Basic information

• Product Name: 5,5-DiMethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-Oxide
• Synonyms: 5,5-DiMethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-Oxide
• CAS NO: 231280-23-2
• Molecular Formula: C₁₁H₁₅O₆P
• Molecular Weight: 274.206961
• Product Categories: Aliphatics, Metabolites & Impurities, Phosphorylating and Phosphitylating Agents
• Mol File: 231280-23-2.mol

Chemical Properties

• Appearance: /
• Solubility: DCM, Methanol
• CAS DataBase Reference: 5,5-DiMethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-Oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-DiMethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-Oxide(231280-23-2)
• EPA Substance Registry System: 5,5-DiMethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-Oxide(231280-23-2)

Safety Data

• Hazardous Substances Data: 231280-23-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5,5-Dimethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-oxide is used as an intermediate in the synthesis of Hydroxypyruvic Acid Phosphate (H953190) for its role in microbial growth. 5,5-dimethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-oxide serves as a crucial building block in the development of pharmaceuticals targeting microbial infections, contributing to the creation of new antibiotics and other therapeutic agents.
Used in Chemical Synthesis:
In the chemical industry, 5,5-dimethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-oxide is utilized as a versatile intermediate for the synthesis of various complex organic molecules. Its unique structure allows for further functionalization and modification, making it a valuable component in the development of new chemical products and materials.
Used in Research and Development:
Due to its unique chemical properties and potential applications, 5,5-dimethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-oxide is also used in research and development settings. Scientists and researchers employ 5,5-dimethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-oxide to explore new reaction pathways, develop novel synthetic methods, and investigate its potential applications in various fields, including pharmaceuticals, materials science, and biotechnology.

Upstream product

• 770-12-7 O-phenyl phosphorodichloridate 
• 153214-82-5 2,2-dimethoxypropane-1,3-diol 

Downstream Products

• 29909-08-8 cyclohexylamine 
• 29909-09-9 phosphoric acid mono-(3-hydroxy-2,2-dimethoxy-propyl ester) 
• 1006694-13-8 cyclohexylammonium 5,5-dimethoxy-2-oxo-1,3,2-dioxaphosphorinan-2-olate 

Relevant articles and documents

5,5-dimethoxy-2-phenoxy-1,3,2-dioxaphosphorinane 2-oxide

In the title compound, C11H15O6P, the six-membered dioxaphosphorinane ring of the cyclic phosphate triester exists in a distorted chair conformation, with the phenoxy group in an axial position. The phenyl ring and both me

Dihydroxyacetone phosphate, DHAP, in the crystalline state: monomeric and dimeric forms

It was shown that dihydroxyacetone phosphate may exist in both monomeric DHAP (C3H7O6P) and dimeric DHAP-dimer (C6H14O12P2) form. Monomeric DHAP was obtained in the form of four crystalline salts: CaCl(DHAP)·2.9H2O (7a), Ca2Cl3(DHAP)·5H2O (7b), CaCl(DHAP)·2H2O (7c), and CaBr(DHAP)·5H2O (7d) by crystallization from aqueous solutions containing DHAP acid and CaCl2 or CaBr2, or by direct crystallization from a solution containing DHAP precursor and CaCl2. At least one of the salts is stable and may be stored in the crystalline state at room temperature for several months. The dimeric form was obtained by slow saturation of free DHAP syrup with ammonia at -18 °C and isolated in the form of its hydrated diammonium salt (NH4)2(DHAP-dimer)·4H2O (8). The synthesis of the compounds, their crystallization, and crystal structures determined by X-ray crystallography are described. In all 7a-d monomeric DHAP exists in the monoanionic form in an extended (in-plane) cisoid conformation, with both hydroxyl and ester oxygen atoms being synperiplanar to the carbonyl O atom. The crucial structural feature is the coordination manner, in which the terminal phosphate oxygen atoms act as chelating as well as bridging atoms for the calcium cations. Additionally, the DHAP monoanions chelate another Ca2+ by the α-hydroxycarbonyl moiety, in a manner observed previously in dihydroxyacetone (DHA) calcium chloride complexes. In dimeric 8 the anion is a trans isomer with the dioxane ring in a chair conformation with the hydroxyl groups in axial positions and the phosphomethyl group in an equatorial position.