231618-94-3

Basic information

• Product Name: (2R,3R,4R,5R)-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine
• Synonyms: (2R,3R,4R,5R)-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine
• CAS NO: 231618-94-3
• Molecular Weight: 474.6
• Mol File: 231618-94-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R,5R)-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5R)-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine(231618-94-3)
• EPA Substance Registry System: (2R,3R,4R,5R)-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine(231618-94-3)

Safety Data

• Hazardous Substances Data: 231618-94-3(Hazardous Substances Data)

Upstream product

• 10543-60-9 2,4,6,8-tetraacetyl-2,4,6,8-tetraazabicyclo<3,3,0>octan-3,7-dione 
• 1049770-50-4 (2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-1-hydroxypyrrolidine-2-carbonitrile 
• 537030-19-6 (2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-3,4-dihydro-2H-pyrrole 1-oxide 
• 231618-86-3 (1''R,2R,3R,4R,5R)-N-butyloxycarbonyl-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>-2-<1,2-dihydroxyethyl>pyrrolidine 
• 231618-90-9 (2R,3R,4R,5R)-3,4-Bis-benzyloxy-2-benzyloxymethyl-5-methanesulfonyloxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 231618-88-5 (2R,3R,4R,5R)-N-butyloxycarbonyl-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>-2-(hydroxymethyl)pyrrolidine 
• 231618-91-0 (2R,3R,4R,5R)-N-butyloxycarbonyl-2-(azidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine 
• 231618-92-1 (2R,3R,4R,5R)-N-butyloxycarbonyl-2-(aminomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine 
• 231618-87-4 (2S,3R,4R,5R)-N-butyloxycarbonyl-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine-2-carbaldehyde 
• 173142-28-4 (1'R,2R,3S,4R,5R)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>-2-<1',2'-dihydroxyethyl>pyrrolidine 
• 231618-93-2 (2R,3R,4R,5R)-N-butyloxycarbonyl-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine 
• 231619-09-3 (2R,3S,4S,5R,6R)-6-azido-2,3-epoxy-4,5,7-tris(benzyloxy)-2(E)-hepten-1-ol 
• 159063-89-5 (2R,3R,4R,5R)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidino<1,2-c>oxazole-3-one 

Downstream Products

• 231618-96-5 (2R,3R,4R,5R)-N-butyl-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine 
• 231618-95-4 (2R,3R,4R,5R)-N-methyl-2-(acetamidomethyl)-3,4-bis(benzyloxy)-5-<(benzyloxy)methyl>pyrrolidine 

Relevant articles and documents

Synthesis of pyrrolidine monocyclic analogues of pochonicine and its stereoisomers: Pursuit of simplified structures and potent β-N-acetylhexosaminidase inhibition

Ten pairs of pyrrolidine analogues of pochonicine and its stereoisomers have been synthesized from four enantiomeric pairs of polyhydroxylated cyclic nitrones. Among the ten N-acetylamino pyrrolidine analogues, only compounds with 2,5-dideoxy-2,5-imino-d-

A versatile synthetic strategy for the preparation and discovery of new iminocyclitols as inhibitors of glycosidases

A series of iminocyclitols was prepared using a versatile synthetic strategy, and their inhibition of glycosidases was evaluated using capillary electrophoresis. The study has demonstrated that remarkable specificities in enzyme inhibition can be achieved with small modifications on the aglycon side chain and the ring nitrogen. Among the compounds synthesized, (2R,3R,4R,5R)-N-methyl-2(acetamidomethyl)-3,4-dihydroxy-5- (hydroxymethyl)pyrrolidine was found to be very potent against β-N- acetylhexosaminidase P with the K(i) value of 80 nM.