23165-19-7

Usage

Uses

Used in Organic Synthesis:
4,4-Dimethylmorpholinium chloride is used as a phase-transfer catalyst for enhancing the efficiency of various organic reactions. Its ability to form ion pairs with reactants allows for easier movement between phases, thus improving the overall reaction rate and selectivity.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 4,4-dimethylmorpholinium chloride serves as a catalyst in the production of various organic compounds. Its role in facilitating phase-transfer reactions is crucial for synthesizing complex organic molecules that are often the active ingredients in pharmaceuticals.
Used in Surfactant and Detergent Production:
4,4-Dimethylmorpholinium chloride is utilized as a catalyst in the synthesis of surfactants and detergents. Its catalytic properties aid in the production of these industrial chemicals, which are essential for a wide range of applications, including cleaning products and personal care items.
Used in Other Industrial Chemical Production:
Beyond its applications in organic synthesis, pharmaceuticals, surfactants, and detergents, 4,4-dimethylmorpholinium chloride also finds use in the production of other industrial chemicals. Its versatility as a phase-transfer catalyst makes it a valuable component in various chemical processes across different industries.

InChI:InChI=1/C6H14NO.ClH/c1-7(2)3-5-8-6-4-7;/h3-6H2,1-2H3;1H/q+1;/p-1

Upstream product

• 109-02-4 4-methyl-morpholine 
• 612-62-4 2-Chloroquinoline 
• 15679-03-5 6-chlorophenanthridine 
• 74-87-3 methylene chloride 
• 124-40-3 dimethyl amine 
• 111-44-4 3-oxa-1,5-dichloropentane 
• 19493-44-8 1-chloroisoquinoline 

Relevant academic research and scientific papers

Synthetic method for co-production of 2-hydroxy-benzonitrile and plant growth regulator

The invention relates to the field of pesticides, and discloses a synthetic method for co-production of 2-hydroxy-benzonitrile and a plant growth regulator. The method comprises the steps of 1) in the presence of an aprotic polar solvent, enabling 2-methoxybenzonitrile and lithium chloride to be subjected to a contact reaction to obtain 2-hydroxy-benzonitrile and chloromethane gas; and (2) carrying out quaternization reaction on the chloromethane gas obtained in the step (1) and a solution containing N-methylpiperidine or a solution containing N-methylmorpholine to obtain mepiquat chloride or mepiquat chloride. The method is green and environment-friendly, mild in reaction condition and simple and convenient to operate, the 2-hydroxy-benzonitrile can be obtained at high yield, and the mepiquat chloride or the sulfonamide is co-produced at the same time, so that zero emission of tail gas is achieved.

Sulfur, oxygen, and nitrogen mustards: Stability and reactivity

Mustard gas, bis(β-chloroethyl) sulfide (HD), is highly toxic and harmful to humans and the environment. It comprises one class of chemical warfare agents (CWAs) that was used in both World Wars I and II. The three basic analogues or surrogates are: the monochloro derivative, known as the half mustard, 2-chloroethyl ethyl sulfide (CEES); an oxygen analogue, bis(β-chloroethyl) ether (BCEE); and several nitrogen analogues based on the 2,2′-dichlorodiethylamine framework (e.g., HN1, HN2, and HN3). The origin of their toxicity is considered to be from the formation of three-membered heterocyclic ions, a reaction that is especially accelerated in aqueous solution. The reaction of these cyclic ion intermediates with a number of important biological species such as DNA, RNA and proteins causes cell toxicity and is responsible for the deleterious effects of the mustards. While a number of studies have been performed over the last century to determine the chemistry of these compounds, early studies suffered from a lack of more sophisticated NMR and X-ray techniques. It is now well-established that the sulfur and nitrogen mustards are highly reactive in water, while the oxygen analog is much more stable. In this study, we review and summarize results from previous studies, and add results of our own studies of the reactivity of these mustards toward various nonaqueous solvents and nucleophiles. In this manner a more comprehensive evaluation of the stability and reactivity of these related mustard compounds is achieved.