23194-66-3 Usage
Uses
Used in Pharmaceutical Industry:
(3-METHOXY-PHENYL)-OXO-ACETONITRILE is used as a key intermediate for the synthesis of various pharmaceuticals, leveraging its nitrile functional group to form a wide range of biologically active compounds. The presence of the methoxy group can also contribute to the alteration of chemical and biological activities in the resulting pharmaceuticals.
Used in Agrochemical Industry:
In the agrochemical sector, (3-METHOXY-PHENYL)-OXO-ACETONITRILE is utilized as a building block for the development of agrochemicals, such as pesticides and herbicides. Its structural features allow for the creation of compounds with specific target activities against pests or weeds, enhancing crop protection strategies.
Used in Organic Synthesis:
(3-METHOXY-PHENYL)-OXO-ACETONITRILE is employed as a versatile reagent in organic synthesis for the preparation of a variety of fine chemicals. Its unique structure facilitates the synthesis of complex molecules with potential applications in various industries, including the fragrance, flavor, and specialty chemical sectors.
Used in Research and Development:
(3-METHOXY-PHENYL)-OXO-ACETONITRILE is also used in research and development settings to explore new synthetic pathways and investigate the effects of structural modifications on chemical and biological properties. Its presence in a molecule can provide insights into structure-activity relationships and guide the design of new compounds with improved performance.
Check Digit Verification of cas no
The CAS Registry Mumber 23194-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,1,9 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23194-66:
(7*2)+(6*3)+(5*1)+(4*9)+(3*4)+(2*6)+(1*6)=103
103 % 10 = 3
So 23194-66-3 is a valid CAS Registry Number.
23194-66-3Relevant academic research and scientific papers
A Cyanide-Free Synthesis of Acylcyanides through Ru-Catalyzed C(sp3)-H-Oxidation of Benzylic Nitriles
Eisele, Pascal,Bauder, Michael,Hsu, Shih-Fan,Plietker, Bernd
, p. 689 - 691 (2019/05/07)
A practical method for generation of acylcyanides devoid of any external cyanide sources is presented that relies on a mild Ru-catalyzed selective C?H-oxidation of benzylic nitriles. The starting materials are smoothly generated through condensation of the corresponding carboxylic acid amides using silanes. The obtained acylcyanides can be employed in a plethora of transformation as exemplified to some larger extend in the sequence of C?H-oxidation-Tischenko-rearrangement for the generation of structurally diverse benzoyloxycyanohydrines.
Rh-Catalyzed Asymmetric Hydrogenation of 1,2-Dicyanoalkenes
Li, Meina,Kong, Duanyang,Zi, Guofu,Hou, Guohua
, p. 680 - 687 (2017/04/26)
A highly efficient enantioselective hydrogenation of 1,2-dicyanoalkenes catalyzed by the complex of rhodium and f-spiroPhos has been developed. A series of 1,2-dicyanoalkenes were successfully hydrogenated to the corresponding chiral 1,2-dicyanoalkanes under mild conditions with excellent enantioselectivities (up to 98% ee). This methodology provides efficient access to the asymmetric synthesis of chiral diamines.
A new convenient synthesis of aroyl cyanides via the formation of cyanohydrin nitrate intermediates
Sueda, Takuya,Shoji, Masashi,Nishide, Kiyoharu
, p. 5070 - 5072 (2008/12/21)
The treatment of α-bromoarylacetonitriles with AgNO3 generates cyanohydrin nitrate intermediates, which easily eliminate nitrous acid with the formation of carbonyl bond to afford aroyl cyanides in good to high yields.
