2322-38-5

Usage

Uses

Used in Chemical Synthesis:
2,3,5,6-Tetrachloro-4-pyridinol is used as a reactant in the tautomerization of pyridone to hydroxypyridine. This tautomerization is an important reaction in the synthesis of various pyridine-based compounds, which have a wide range of applications in the chemical and pharmaceutical industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3,5,6-tetrachloro-4-pyridinol can be used as a building block for the development of new drugs. Its unique structure and reactivity make it a valuable starting material for the synthesis of various bioactive compounds with potential therapeutic applications.
Used in Agrochemical Industry:
2,3,5,6-Tetrachloro-4-pyridinol may also find applications in the agrochemical industry as a precursor for the synthesis of pesticides or other agrochemical products. Its chemical properties can be exploited to create compounds with specific biological activities, targeting pests or diseases affecting crops.
Used in Research and Development:
Due to its unique structure and reactivity, 2,3,5,6-tetrachloro-4-pyridinol can be a valuable compound for research and development purposes. It can be used in the design and synthesis of new materials, catalysts, or other specialty chemicals that may have various applications in different industries.

Upstream product

• 2176-62-7 2,3,4,5,6-pentachloropyridine 
• 856969-26-1 heptachloro-2,3-dihydro-1H-pyridin-4-one 
• 865-47-4 potassium tert-butylate 
• 81706-73-2 1-bromo-2-tetrachloro-4-pyridyloxyethane 
• 81706-70-9 1-bromo-3-tetrachloro-4-pyridyloxypropane 
• 32124-70-2 potassium tetrachloropyridin-4-olate 
• 81706-88-9 tetrachloro-4-propoxypyridine 
• 88279-36-1 1-benzyl-1,1-dimethylhydrazinium 2,3,5,6-tetrachloropyridin-4-olate 
• 73057-83-7 allyl 2,3,5,6-tetrachloro-4-pyridyl ether 
• 17228-76-1 2,3,5,6-tetrachloro-4-ethoxypyridine 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 
• 81726-44-5 4-{3-[(2,3,5,6-tetrachloropyridin-4-yl)oxy]propoxy}-2,3,5,6-tetrachloropyridine 

Downstream Products

• 86816-07-1 4-benzyloxytetrachloropyridine 
• 88279-36-1 1-benzyl-1,1-dimethylhydrazinium 2,3,5,6-tetrachloropyridin-4-olate 
• 88279-39-4 2,3,5,6-Tetrachloro-pyridin-4-olatebenzyl-triethyl-ammonium; 
• 88279-37-2 2,3,5,6-Tetrachloro-pyridin-4-olatebenzyl-(2-dimethylamino-ethyl)-dimethyl-ammonium; 

Relevant academic research and scientific papers

A facile and convenient method for the synthesis of nitro phenols and chloropyridinols

An efficient, simple, and practical method of preparation of nitro phenols and chloropyridinols has been reported by the active chlorine displacement of chloro nitro benzenes and poly chloro pyridines in the presence of alkali metal hydroxide in low polarity solvent with very good yields.

Polyhalogenoaromatic Compounds. Part 50. Reactions of 4-Benzyloxytetrahalogenopyridines with Nucleophiles

Reaction of 4-benzyloxy-3,5-dichloro-2,6-difluoro- (1; R = CH2Ph) and 4-benzyloxytetrachloropyridine (2; R = CH2Ph) with various nucleophiles (N,N-dimethylhydrazine, piperidine, N,N,N',N'-tetramethylethane-1,2-diamine, triphenylphosphine) occurs unexpectedly at the benzylic methylene group with alkyl-oxygen cleavage to give the corresponding benzylammonium (4) or triphenylphosphonium salt (9) respectively.The molecular structure of the salt derived from 4-benzyloxytetrachloropyridine and N,N-dimethylhydrazine was confirmed by an X-ray study.Preliminary experiments of ut ilising the benzyl cleavage for the preparation of various benzyl derivatives (PhCH2X; X = Cl,Br,I,CN,N3) are described.

Polyhalogenoaromatic Compounds. Part 46. Circumstantial Evidence for the Intermediacy of Radical Anions during the Reaction of Magnesium with ω-Bromoalkoxypolychloro-arenes and -heteroarenes

4-(ω-Bromoalkoxy)tetrachloropyridines, 4-(ω-bromoalkoxy)-3,5-dichloro-2,6-difluoropyridines, and (ω-bromoalkoxy)-pentachlorobenzenes have been prepared by reaction of the appropriate aryl and heteroaryl oxides with 1,ω-dibromoalkanes.The main products from the reactions of the bromoethoxy- or bromopropoxy-tetrachloropyridines with magnesium were the furopyridine (9a) and pyranopyridine (9b), respectively.Elimination of other possible reaction pathways leads to the hypothesis that the cyclisations proceed by electron transfer from magnesium to the tetrachloropyridyl group, followed by nucleophilic displacement of bromide from the side chain.In the absence of a leaving group in the side chain, the radical-anion intermediate leads to a Grignard reagent.