2322-38-5Relevant articles and documents
A facile and convenient method for the synthesis of nitro phenols and chloropyridinols
Raju, B. China,Neelakantan, Parvathi,Bhalerao
, p. 2903 - 2909 (2007/10/03)
An efficient, simple, and practical method of preparation of nitro phenols and chloropyridinols has been reported by the active chlorine displacement of chloro nitro benzenes and poly chloro pyridines in the presence of alkali metal hydroxide in low polarity solvent with very good yields.
Polyhalogenoaromatic Compounds. Part 50. Reactions of 4-Benzyloxytetrahalogenopyridines with Nucleophiles
Julia, Louis,Suschitzky, H.,Barnes, John C.,Tomlin, Clive D.S.
, p. 2507 - 2511 (2007/10/02)
Reaction of 4-benzyloxy-3,5-dichloro-2,6-difluoro- (1; R = CH2Ph) and 4-benzyloxytetrachloropyridine (2; R = CH2Ph) with various nucleophiles (N,N-dimethylhydrazine, piperidine, N,N,N',N'-tetramethylethane-1,2-diamine, triphenylphosphine) occurs unexpectedly at the benzylic methylene group with alkyl-oxygen cleavage to give the corresponding benzylammonium (4) or triphenylphosphonium salt (9) respectively.The molecular structure of the salt derived from 4-benzyloxytetrachloropyridine and N,N-dimethylhydrazine was confirmed by an X-ray study.Preliminary experiments of ut ilising the benzyl cleavage for the preparation of various benzyl derivatives (PhCH2X; X = Cl,Br,I,CN,N3) are described.