23234-97-1

Usage

InChI:InChI=1/C18H14Cl5NO6/c1-28-9-4-2-8(3-5-9)7-29-18(27)24-10(6-25)17(26)30-16-14(22)12(20)11(19)13(21)15(16)23/h2-5,10,25H,6-7H2,1H3,(H,24,27)

Upstream product

• 74401-62-0 ethyl 2-chloro-3-(4-hydroxyphenyl)propionate 
• 74401-65-3 ethyl 2-azido-3-(4-hydroxyphenyl)propionate 
• 100-00-5 4-chlorobenzonitrile 
• 62516-91-0 ethyl 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)phenyl]propionate 
• 62516-93-2 2-chloro-3-<4-(2-methyl-2-phenylpropyloxy)phenyl>propionic acid 
• 62517-30-0 4-(2-methyl-2-phenylpropyloxy)aniline 
• 62517-29-7 4-(2-methyl-2-phenylpropyloxy)nitrobenzene 

Downstream Products

• 77693-87-9 Z(OMe)-Ser-Ile-Thr-OMe 
• 77693-89-1 Z(OMe)-Ser-Thr-Met-OMe 
• 77834-30-1 Z(OMe)-Ser-Lys(Z)-Tyr-OMe 
• 77834-31-2 Z(OMe)-Ser-Ser-Lys(Z)-Tyr-OMe 
• 78075-42-0 Z(OMe)-Ser-Ala-Ala-NHNH-Troc 
• 76061-35-3 Z(OMe)-Ser-Ile-Thr-NHNH₂ 

Relevant academic research and scientific papers

Studies on antihyperlipidemic agents. III. Synthesis and biological activities of 2-chloro-3-arylpropionic acids containing a quarternary carbon atom

A series of 2-chloro-3-(4-alkoxyphenyl)propionic acids containing a quarternary carbon atom in the alkoxy moiety was prepared and the hypolipidemic and hypoglycemic activities were evaluated. Of the 18 compounds synthesized, ethyl 2-chloro-3-[4-(2-methyl-2-phenylpropyloxy)phenyl]propionate was the best with respect to biological activity and toxicity. Its functional derivatives and optically resolved enantiomers were also prepared. Structure-activity relationships are discussed briefly.