23240-49-5Relevant articles and documents
Discovery of tetrahydrocarbazoles as dual pERK and pRb inhibitors
Kulkarni, Mahesh R.,Mane, Madhav S.,Ghosh, Usha,Sharma, Rajiv,Lad, Nitin P.,Srivastava, Ankita,Kulkarni-Almeida, Asha,Kharkar, Prashant S.,Khedkar, Vijay M.,Pandit, Shivaji S.
, p. 366 - 378 (2017/04/24)
The extracellular signal-regulated kinase (ERK) is one of the most important molecular targets for cancer that controls diverse cellular processes such as proliferation, survival, differentiation and motility. Similarly, the Rb (retinoblastoma protein) is