23246-19-7Relevant articles and documents
An improved and green preparation of 3-(alkylthio)propionic acids
Vaismaa, Matti J. P.,Yliniemel?, Sanna M.,Lajunen, Marja K.
, p. 1317 - 1323 (2008/10/09)
An efficient, facile microwave-assisted synthesis has been developed for the preparation of unsymmetrical sulfide derivatives from 3-mercaptopropionic acid and a wide variety of alkyl, allyl or aryl chlorides or bromides. The synthesis performed in ethanol at 80 or 120 °C using sodium hydroxide as a base, selectively without an offensive smell, generates 3-(alkylthio)propionic acids in good yields. Effects of reaction components, temperature, and the heating technique on the formation of the product and side-products were studied.
