232595-59-4

Usage

Uses

Used in Pharmaceutical Industry:
3-[(tert-Butoxycarbonyl)amino]-5-hydroxybenzoic acid is used as a reactant for the preparation of thiazolecarboxamides, which are known as vitronectin receptor antagonists. These antagonists play a crucial role in inhibiting the vitronectin receptor, a protein involved in various biological processes, including cell adhesion, migration, and wound healing. By targeting the vitronectin receptor, thiazolecarboxamides can potentially be used in the development of therapeutic agents for conditions such as cancer, where the inhibition of this receptor can help prevent tumor growth and metastasis.

InChI:InChI=1/C12H15NO5/c1-12(2,3)18-11(17)13-8-4-7(10(15)16)5-9(14)6-8/h4-6,14H,1-3H3,(H,13,17)(H,15,16)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 76045-71-1 3-amino-5-hydroxybenzoic acid 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 14206-69-0 3-amino-5-hydroxybenzoic acid hydrochloride 

Relevant academic research and scientific papers

NOVEL GLUCOKINASE ACTIVATORS AND PROCESSES FOR THE PREPARATION THEREOF

The present invention provides an amide derivative having a stilbene or 1,2-diphenylethane moiety within the molecule thereof, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The amide derivative of the present

Thiazole derivatives

Compounds of the formula: as well as pharmaceutically usable salts and esters thereof, wherein R1, R2and R3have the significance ascribed herein, inhibit binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. These compounds can be used in the form of pharmaceutical preparations for the control or prevention of neoplasms, tumor metastasing, tumor growth, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, fibrosis, kidney failure, as well as infection caused by viruses, bacteria or fungi.

Thiazole derivatives

Compounds of the formula: as well as pharmaceutically usable salts and esters thereof, wherein R1, R2 and R3 have the significance ascribed herein, inhibit binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. These compounds can be used in the form of pharmaceutical preparations for the control or prevention of neoplasms, tumor metastasing, tumor growth, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, fibrosis, kidney failure, as well as infection caused by viruses, bacteria or fungi.