23277-04-5

Basic information

• Product Name: 2-BENZYLISOQUINOLINIUM BROMIDE
• Synonyms: 2-BENZYLISOQUINOLINIUM BROMIDE;2-benzylisoquinolin-2-ium:bromide
• CAS NO: 23277-04-5
• Molecular Formula: Br*C₁₆H₁₄N
• Molecular Weight: 300.19
• Mol File: 23277-04-5.mol
• Article Data: 17

Chemical Properties

• Melting Point: 110-111.5 °C
• Appearance: /
• CAS DataBase Reference: 2-BENZYLISOQUINOLINIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYLISOQUINOLINIUM BROMIDE(23277-04-5)
• EPA Substance Registry System: 2-BENZYLISOQUINOLINIUM BROMIDE(23277-04-5)

Safety Data

• Hazardous Substances Data: 23277-04-5(Hazardous Substances Data)

Usage

General Description

2-Benzylisoquinolinium bromide is a chemical compound with the molecular formula C21H20NBr. It is a quaternary ammonium salt that is used as a pharmaceutical intermediate in the synthesis of organic compounds. 2-BENZYLISOQUINOLINIUM BROMIDE is research-grade and is used in biochemical research and drug development. It is also used in the preparation of anti-cancer and anti-inflammatory drugs. 2-Benzylisoquinolinium bromide has been studied for its potential pharmacological properties and has been found to exhibit antitumor and antimicrobial activities. It is a highly specialized chemical that is primarily used in laboratory and research settings for various applications.

InChI:InChI=1/C16H14N.BrH/c1-2-6-14(7-3-1)12-17-11-10-15-8-4-5-9-16(15)13-17;/h1-11,13H,12H2;1H/q+1;/p-1

Upstream product

• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 119-65-3 isoquinoline 
• 100-39-0 benzyl bromide 

Downstream Products

• 855716-63-1 2-(α'-hydroxy-2'-nitro-bibenzyl-α-yl)-isoquinolinium betaine 
• 13605-95-3 N-benzyl-1,2,3,4-tetrahydroisoquinoline 
• 104889-68-1 N-benzyl-1,2-dihydroisoquinoline 
• 141341-97-1 8-phenylbenzo[5,6]isoindolo[1,2-a]isoquinoline-9,14-dione 
• 22990-19-8 1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 789429-17-0 N-benzyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

Copper-Catalyzed Selective 1,2-Dialkylation of N-Heteroarenes via a Radical Addition/Reduction Process: Application for the Construction of Alkylated Dihydroazaarenes Derivatives

A highly efficient Cu-catalyzed 1,2-difunctionalization of various N-heteroarenes was developed with ether and alkyl halide at ambient temperature. This transformation involves the combination of oxidative coupling by Cu/TBHP and reduction process by 1,8-

Covalent Organic Frameworks toward Diverse Photocatalytic Aerobic Oxidations

Photoactive two-dimensional covalent organic frameworks (2D-COFs) have become promising heterogenous photocatalysts in visible-light-driven organic transformations. Herein, a visible-light-driven selective aerobic oxidation of various small organic molecules by using 2D-COFs as the photocatalyst was developed. In this protocol, due to the remarkable photocatalytic capability of hydrazone-based 2D-COF-1 on molecular oxygen activation, a wide range of amides, quinolones, heterocyclic compounds, and sulfoxides were obtained with high efficiency and excellent functional group tolerance under very mild reaction conditions. Furthermore, benefiting from the inherent advantage of heterogenous photocatalysis, prominent sustainability and easy photocatalyst recyclability, a drug molecule (modafinil) and an oxidized mustard gas simulant (2-chloroethyl ethyl sulfoxide) were selectively and easily obtained in scale-up reactions. Mechanistic investigations were conducted using radical quenching experiments and in situ ESR spectroscopy, all corroborating the proposed role of 2D-COF-1 in photocatalytic cycle.

Co(iii)-catalysed regioselective linear C(8)-H olefination of isoquinolone with terminal aromatic and aliphatic alkynes

A regioselective C8 linear olefination of isoquinoline-1H-2-one with terminal (aromatic and aliphatic) alkynes is reported under Co(iii) catalysis. This is an exclusive report on the C8 functionalization of isoquinolone using non-noble transition metal co