232926-11-3Relevant academic research and scientific papers
Inhibition of the FAD containing ER oxidoreductin 1 (Ero1) protein by EN-460 as a strategy for treatment of multiple myeloma
Hayes, Karen E.,Batsomboon, Paratchata,Chen, Wei-Chih,Johnson, Brennan D.,Becker, Andreas,Eschrich, Steven,Yang, Yan,Robart, Aaron R.,Dudley, Gregory B.,Geldenhuys, Werner J.,Hazlehurst, Lori A.
, p. 1479 - 1488 (2019/03/06)
Multiple myeloma (MM) cells demonstrate high basal endoplasmic reticulum (ER) stress and are typically exquisitely sensitive to agents such as proteasome inhibitors that activate the unfolded protein response. The flavin adenosine dinucleotide (FAD) conta
[3H]Azidodantrolene: synthesis and use in identification of a putative skeletal muscle dantrolene binding site in sarcoplasmic reticulum.
Palnitkar,Bin,Jimenez,Morimoto,Williams,Paul-Pletzer,Parness
, p. 1872 - 1880 (2007/10/03)
Dantrolene sodium is a medically important hydantoin derivative that interferes with release of Ca2+ from intracellular stores of skeletal muscle by an unknown mechanism. Identification of the molecular target of dantrolene would greatly aid in understand
