232944-73-9Relevant academic research and scientific papers
Dimethyl sulfide-boron trihalide-mediated reactions of α,β-unsaturated ketones with aldehydes: One-pot synthesis of Baylis-Hillman adducts and α-halomethyl enones
Iwamura, Tatsunori,Fujita, Masaru,Kawakita, Tetsuya,Kinoshita, Sayaka,Watanabe, Shin-Ichi,Kataoka, Tadashi
, p. 8455 - 8462 (2007/10/03)
The reactions of aldehydes with 3-buten-2-one (2) were conducted in the presence of BBr3·Me2S or BCl3·Me2S and then worked up with aqueous NaHCO3, affording the α-methylene aldol 3, α-halomethyl aldol 4 or 6, and α-halomethyl enones 5 or 7, respectively. In contrast, the reactions quenched with water gave the α-halomethyl enones 5 or 7 in high yields, while the work-up with an aqueous 10% trimethylamine gave the α-methylene aldol 3. The phenol 15 and half-acetal 16 were obtained from the reaction of p-nitrobenzaldehyde (1a) with cyclohexenone (10).
Baylis-Hillman chemistry: A novel synthesis of functionalized 1,4-pentadienes
Basavaiah, Deevi,Kumaragurubaran, Nagaswamy,Sharada, Duddu S.
, p. 85 - 87 (2007/10/03)
A novel synthesis of functionalized 1,4-pentadienes via the reaction of acrylonitrile with allyl halides, derived from Baylis-Hillman adducts, in the presence of DABCO has been described, demonstrating for the first time the application of allyl halides a
The Baylis-Hillman reaction: An expedient synthesis of (Z)-keto allyl bromides and chlorides
Basavaiah, Deevi,Hyma, Rachakonda Suguna,Padmaja, Kisari,Krishnamacharyulu, Marimganti
, p. 6971 - 6976 (2007/10/03)
A simple and expedient synthesis of (Z)- keto allyl bromides and chlorides, from the Baylis-Hillman adducts is described.
