232950-90-2

Basic information

• Product Name: Acetamide, N-[[(5S)-3-(3-fluoro-4-formylphenyl)-2-oxo-5-oxazolidinyl]methyl]-
• CAS NO: 232950-90-2
• Molecular Formula: C13H13FN2O4
• Molecular Weight: 280.256
• Mol File: 232950-90-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[[(5S)-3-(3-fluoro-4-formylphenyl)-2-oxo-5-oxazolidinyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[[(5S)-3-(3-fluoro-4-formylphenyl)-2-oxo-5-oxazolidinyl]methyl]-(232950-90-2)
• EPA Substance Registry System: Acetamide, N-[[(5S)-3-(3-fluoro-4-formylphenyl)-2-oxo-5-oxazolidinyl]methyl]-(232950-90-2)

Safety Data

• Hazardous Substances Data: 232950-90-2(Hazardous Substances Data)

Upstream product

• 1428246-76-7 5-(S)-acetamidomethyl-3-[4'-dimethoxymethyl-3'-fluorophenyl]-oxazolidine-2-one 
• 403-24-7 2-fluoro-4-nitrobenzoic acid 
• 1427-07-2 2-fluoro-4-nitrotoluene 
• 100-97-0 hexamethylenetetramine 
• 139071-79-7 (S)-N-[[3-(3-fluorophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamide 
• 840501-17-9 [4-(tert-butyl-dimethyl-silanyloxymethyl)-3-fluoro-phenyl]-carbamic acid benzyl ester 
• 840501-16-8 (3-fluoro-4-hydroxymethyl-phenyl)-carbamic acid benzyl ester 
• 840501-15-7 (4-amino-2-fluorophenyl)methanol 
• 73792-08-2 methyl 4-amino-2-fluorobenzoate 
• 392-09-6 2-fluoro-4-nitro-benzoic acid methyl ester 

Relevant articles and documents

The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinones

A series of oxazolidinone antibacterial agents containing a 5-substituted isoxazol-3-yl moiety were synthesized via a nitrile oxide [3+2] dipolar cycloaddition reaction. These compounds were screened against a panel of susceptible and resistant Gram-positive organisms. Several analogs from this series were comparable to or more potent than linezolid in vitro.

Oxazolidinone combinatorial libraries, compositions and methods of preparation

Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.