233281-31-7Relevant articles and documents
Effect of the linkages on the self-assembly and photophysical properties of 4,7-diphenyl-2,1,3-benzothiadiazole-based luminescent polycatenars
Hu, Jinliang,Xiao, Yulong,Chang, Qing,Gao, Hongfei,Cheng, Xiaohong
, (2019/05/10)
Three series of 4,7-diphenyl-2,1,3-benzothiadiazole (DBTD)based polycatenars containing a central 4,7-diphenyl-2,1,3-benzothiadiazole moiety connected to 3,4,5-trialkoxyl benzene units at both ends through ether (-OCH2-), ester (-OOC-)or amide (-HNCO-)linkages were synthesized via Suzuki coupling reaction as key step. The polarities of the linkages had great effect on their self-assembly and photophycial properties. Both ether and amide compounds were mesogens, while the ester compounds were non-mesogens. The ether compounds displayed Colhex/p6mm phases, while the amide compound displayed two kinds of columnar phases i.e. columnar rectangular phase with p2mm and columnar hexagonal phase with p6mm lattices depending on temperature. The column phases could be aligned in electric field or under mechanical shearing. The ether and amide compounds showed the significant red-shifted maximum absorption and emission. In the solid and gel states, both ether and amide compounds were yellow luminescence, while ester compounds were green luminescence.
Rational Design of Supramolecular Dynamic Protein Assemblies by Using a Micelle-Assisted Activity-Based Protein-Labeling Technology
Sandanaraj, Britto S.,Reddy, Mullapudi Mohan,Bhandari, Pavankumar Janardhan,Kumar, Sugam,Aswal, Vinod K.
, p. 16085 - 16096 (2018/10/15)
The self-assembly of proteins into higher-order superstructures is ubiquitous in biological systems. Genetic methods comprising both computational and rational design strategies are emerging as powerful methods for the design of synthetic protein complexes with high accuracy and fidelity. Although useful, most of the reported protein complexes lack a dynamic behavior, which may limit their potential applications. On the contrary, protein engineering by using chemical strategies offers excellent possibilities for the design of protein complexes with stimuli-responsive functions and adaptive behavior. However, designs based on chemical strategies are not accurate and therefore, yield polydisperse samples that are difficult to characterize. Here, we describe simple design principles for the construction of protein complexes through a supramolecular chemical strategy. A micelle-assisted activity-based protein-labeling technology has been developed to synthesize libraries of facially amphiphilic synthetic proteins, which self-assemble to form protein complexes through hydrophobic interaction. The proposed methodology is amenable for the synthesis of protein complex libraries with molecular weights and dimensions comparable to naturally occurring protein cages. The designed protein complexes display a rich structural diversity, oligomeric states, sizes, and surface charges that can be engineered through the macromolecular design. The broad utility of this method is demonstrated by the design of most sophisticated stimuli-responsive systems that can be programmed to assemble/disassemble in a reversible/irreversible fashion by using the pH or light as trigger.
PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED
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Paragraph 0536; 0537, (2017/11/29)
Precipitation promoters, which are an organic compound having one or more linear aliphatic hydrocarbon groups having not less than 10 carbon atoms, wherein the aliphatic hydrocarbon group has not less than 20 carbon atoms in total are useful for precipita
