23343-06-8

Basic information

• Product Name: 2-(ALLYLOXY)-3-METHOXYBENZENECARBALDEHYDE
• Synonyms: 3-methoxy-2-prop-2-enoxybenzaldehyde;3-methoxy-2-prop-2-enoxy-benzaldehyde;ASINEX-REAG BAS 09975907;2-(ALLYLOXY)-3-METHOXYBENZENECARBALDEHYDE;AKOS 92089;TIMTEC-BB SBB010869;benzaldehyde, 3-methoxy-2-(2-propenyloxy)-
• CAS NO: 23343-06-8
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Mol File: 23343-06-8.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 306.4 °C at 760 mmHg
• Flash Point: 130 °C
• Appearance: /
• Density: 1.084 g/cm³
• Vapor Pressure: 0.000774mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: 2-(ALLYLOXY)-3-METHOXYBENZENECARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(ALLYLOXY)-3-METHOXYBENZENECARBALDEHYDE(23343-06-8)
• EPA Substance Registry System: 2-(ALLYLOXY)-3-METHOXYBENZENECARBALDEHYDE(23343-06-8)

Safety Data

• Statements: 36/37/38
• Safety Statements: 36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 23343-06-8(Hazardous Substances Data)

Usage

General Description

2-(allyloxy)-3-methoxybenzenecarbaldehyde is a chemical compound with a molecular formula C12H12O3. It is a derivative of benzaldehyde and contains an aldehyde group, a methoxy group, and an allyloxy group attached to a benzene ring. 2-(ALLYLOXY)-3-METHOXYBENZENECARBALDEHYDE is commonly used in the synthesis of various organic compounds and as a building block in organic chemistry. It may also have potential applications in the pharmaceutical and flavor industries due to its aromatic properties and functional groups. Additionally, 2-(allyloxy)-3-methoxybenzenecarbaldehyde may have biological activities and is an interesting candidate for further research and development.

InChI:InChI=1/C11H12O3/c1-3-7-14-11-9(8-12)5-4-6-10(11)13-2/h3-6,8H,1,7H2,2H3

Upstream product

• 556-56-9 allyl iodid 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 78166-97-9 2-hydroxy-3-methoxybenzaldehyde sodium salt 
• 106-95-6 allyl bromide 

Downstream Products

• 127983-47-5 ethyl α-azido-2-(allyloxy)-3-methoxy-cinnamate 
• 170457-18-8 2-[1-(2-Allyloxy-3-methoxy-phenyl)-meth-(E)-ylidene]-pent-4-enoic acid ethyl ester 
• 200355-11-9 2-Allyloxy-1-methoxy-3-vinyl-benzene 
• 894771-74-5 2-allyloxy-1-(cyclopropylidenemethyl)-3-methoxybenzene 
• 102131-77-1 2,2,5,5-Tetramethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid [3-(2-allyloxy-3-methoxy-benzylamino)-propyl]-amide 
• 1159707-79-5 (2-allyloxy-3-methoxyphenyl)phenylmethanol 
• 1159707-83-1 (2'-allyloxy-3'-methoxyphenyl)-(2''-methoxyphenyl)methanol 
• 1159707-82-0 (2'-allyloxy-3'-methoxyphenyl)-(4''-methoxyphenyl)methanol 
• 1555819-53-8 N,N'-bis(5-allyl-3-methoxysalicylidene)cyclohexane-1,2-diamine 
• 71186-63-5 2-allyloxy-3-methoxy-phenol 
• 22934-51-6 5-allyl-2-hydroxy-3-methoxybenzaldehyde 
• 23354-77-0 2-Allyloxy-3-methoxy-benzaldehyd-dimethylacetal 
• 23343-05-7 1-<2-Allyloxy-3-methoxy-phenyl>-aethanol 
• 579-60-2 6-allylguaicol 

Relevant articles and documents

Hydride transfer reactions of 5-(2-alkohybenzylidene) barbituric acids: Synthesis of 2,4,6-trioxoperhydropyrimidine-5-spiro-3′-chromanes

The thermal cyclization of 5-(2-phenoxymethylphenyl-methylene)barbituric acid and its derivatives affords 2,4,6-trioxoperhydropyrimidine-5-spiro-3′-chromanes. The reactions require no catalysts and proceed at temperatures from 118 to 240?°C depending on the substrate activity. These cyclization reactions are analogous to T-reactions of tertiary amines involving the hydride transfer.

A cascade Claisen rearrangement/o-quinone methide formation/electrocyclization approach to 2H-chromenes

A new approach has been developed for the synthesis of 8-substituted 2H-chromenes, featuring a novel cascade aromatic Claisen rearrangement/o-quinone methide formation/6π-electrocyclization. This new method was demonstrated with 28 examples tolerating different substitutions at alkenes, allylic and aromatic ring and with total syntheses of three 2H-chromene natural products.

The Synthesis of 5-Amino-dihydrobenzo[b]oxepines and 5-Amino-dihydrobenzo[b]azepines via Ichikawa Rearrangement and Ring-Closing Metathesis

The combination of Ichikawa's rearrangement and a ring-closing metathesis reaction of allyl carbamates is presented as a method for the preparation of 5-amino-substituted 2,5-dihydro-benzo[b]oxepines, 2,5-dihydro-benzo[b]azepines, and 2,5-dihydro-benzo[b]thiepins. It was demonstrated that the use of nonracemic allyl carbamates enables the synthesis of enantioenriched benzo-fused seven-membered heterocycles. Finally, it was shown that further functionalization of the obtained structures allows access to pharmacologically active 5-amino-substituted 2,3,4,5-tetrahydro-1-benzo[b]oxepine scaffolds.