233609-24-0Relevant articles and documents
Synthetic studies toward ansatrienines: Application of the Evans- Tishchenko reaction to chiral enones
Schoening, Kai-Uwe,Hayashi,Powell, Douglas R.,Kirschning, Andreas
, p. 817 - 820 (2007/10/03)
Practical syntheses of the C9-C14 sterotriade 5 and the C1-C8 polyene unit 6 in ansatrienine A (mycotriene) (1a), and other ansamycin antibiotics is described. A key step for controlling the configuration of the stereogenic center at C13 involves the stereoselective reduction of enone 10 using the Evans-Tishchenko reaction.