23384-08-9

Upstream product

• 19798-81-3 2-Amino-6-bromopyridine 
• 145100-50-1 1,1,1-trifluoro-N-(pyridin-2-yl)-N-((trifluoromethyl)sulfonyl)methane sulfonamide 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 591-19-5 m-Bromoaniline 

Downstream Products

• 39166-62-6 C,C,C-Trifluoro-N-[3-(toluene-2-sulfonyl)-phenyl]-methanesulfonamide 
• 37950-17-7 3-(4-Chlorphenylsulfonyl)-trifluormethansulfonanilid 
• 37950-21-3 3-(4-Chlorphenylsulfinyl)-trifluormethansulfonanilid 
• 37924-03-1 3-(2-Methylphenylthio)-trifluormethansulfonanilid 
• 37923-99-2 3-(4-Chlorphenylthio)-trifluormethansulfonanilid 
• 37924-01-9 3-(3-Methylphenylthio)-trifluormethansulfonanilid 
• 37924-00-8 3-(4-Fluorphenylthio)-trifluormethansulfonanilid 

Relevant academic research and scientific papers

Diamination of Domino Aryne Precursor with Sulfonamides

The reaction of a domino aryne precursor with sulfonamides efficiently afforded both 1,3-diaminobenzenes and trisubstituted 1,3-diaminobenzenes by simply varying the reaction conditions. Mechanistic study supports the sequential formation of two transient aryne intermediates involved in the reaction.

N '-trifluoromethylsulfonyl N heteroaromatic amine compound and preparation method thereof

The invention discloses an N '-trifluoromethanesulfonyl N-heteroaromatic amine compound and a preparation method of the N'-trifluoromethanesulfonyl N-heteroaromatic amine compound. The preparation method comprises the following steps that: under the protection of inert gas, N-heteroaryl ammonia taken as a raw material reacts with 2-[N, N-bis (trifluoromethanesulfonyl) amino] pyridine in an anhydrous aprotic solvent, so as to obtain the N '-trifluoromethanesulfonyl N-heteroaromatic amine compound with high yield. The preparation method provided by the invention has the characteristics of simpleprocess, wide substrate selection range and high yield. The technical process provided by the invention is simple and is wide in substrate selection range; a post-treatment purification mode is simple, convenient and effective; and the N '-trifluoromethylsulfonyl N heteroaromatic amine compound can be obtained with high efficiency, high yield and high purity.

Chiral proline sulfonamide bifunctional catalyst and preparation method and application thereof

The invention discloses a novel chiral sulfonamide bifunctional catalyst and a preparation method and application thereof. The catalyst comprises a compound A or a compound B. The molecular structureof the compound A is shown as a formula (I) which is des

Substituted benzyl pyrimidines

Compounds of the formula: STR1 in which R1 is lower alkoxy, R2 is bromine or lower alkoxy, and R3 is aryl, heteroaryl or a group --Q--R30, wherein Q is ethylene, vinylene or ethynylene and R30 is aryl, heteroaryl, lower alkoxycarbonyl or carbamoyl; hydrolyzable esters of carboxylic acids of formula I; and pharmaceutically acceptable salts of these compounds are useful for treating infectious diseases.