23471-45-6

Usage

Amine compound

A compound containing a nitrogen atom bonded to carbon atoms 1-methyl-2-p-chlorophenoxyethylamine is an amine compound due to the presence of a nitrogen atom bonded to carbon atoms in its structure.

Methyl group attached to nitrogen

A methyl group (CH3) is attached to the nitrogen atom In the structure of 1-methyl-2-p-chlorophenoxyethylamine, a methyl group is directly bonded to the nitrogen atom, which influences its chemical properties and reactivity.

Chlorine atom attached to the para position of the phenyl ring

A chlorine atom (Cl) is attached to the phenyl ring at the para position (opposite side) The presence of a chlorine atom at the para position of the phenyl ring in 1-methyl-2-p-chlorophenoxyethylamine affects its reactivity, stability, and potential applications.

Organic synthesis

Commonly used in organic synthesis 1-methyl-2-p-chlorophenoxyethylamine is frequently used as a building block or intermediate in the synthesis of more complex organic compounds.

Pharmaceutical and agrochemical production

Used as a building block for the production of various pharmaceuticals and agrochemicals Due to its unique structure and reactivity, 1-methyl-2-p-chlorophenoxyethylamine is employed in the production of a wide range of pharmaceuticals and agrochemicals.

Potential applications in drug development

Has potential applications in the development of new drugs, particularly in the field of neuroscience and psychiatric research The unique structure and properties of 1-methyl-2-p-chlorophenoxyethylamine make it a promising candidate for the development of new drugs, especially in areas related to the nervous system and mental health.

Production of surfactants and industrial chemicals

Used in the production of surfactants and other industrial chemicals 1-methyl-2-p-chlorophenoxyethylamine is also utilized in the manufacturing of surfactants, which are compounds that reduce the surface tension of liquids, and other industrial chemicals with various applications.

Diverse potential applications

Has various potential applications in both academic research and industrial processes The versatility of 1-methyl-2-p-chlorophenoxyethylamine allows it to be used in a wide range of applications, from scientific research to industrial production.

Upstream product

• 104864-65-5 4-chlorophenoxyacetone oxime 
• 18859-35-3 4-chlorophenoxyacetone 
• 106-48-9 4-chloro-phenol 

Downstream Products

• 146016-18-4 1-(4-chlorophenoxy)-2-propyl isocyanate 

Relevant academic research and scientific papers

A (different) bright ammonia amide carbamate derivative and application thereof (by machine translation)

The invention belongs to the field of plant, relates to a general formula (I) is shown in a (different) bright ammonia amide carbamate derivatives and their pharmaceutically acceptable salt, wherein substituent R has the definition given in the specification, the invention also relates to the general formula (I) preparation of compounds of the, specifically for the preparation of the intermediate of its development and application of plant disease control. (by machine translation)

Design, synthesis and effect of the introduction of a propargyloxy group on the fungicidal activities of 1-substituted phenoxypropan-2-amino valinamide carbamate derivatives

The cell walls of oomycetes are composed of cellulose, making cellulose synthase enzymes good targets for carboxylic acid amide fungicides. Valinamide carbamates are amino acid fungicides that represent excellent alternatives to conventional synthetic pesticides in terms of their ability to reduce the negative impacts of these compounds on human health and the environment. In a continuation of our research towards the development of new cellulose synthase inhibitors, we have developed a series of "stretched" analogues of iprovalicarb by the introduction of an additional OCH2 linker. The bioassay results indicated that compounds containing a small group at the para-position of phenyl gave excellent fungicidal activities with EC50 values ranging from 0.59 to 2.06 μmol L-1. Most notably, the introduction of a propargyloxy group led to a pronounced increase in the fungicidal activity. Furthermore, compound 7o bearing a propargyloxy group was identified as the most promising candidate because of its excellent fungicidal potency against oomycete diseases and good fungicidal activity against non-oomycete diseases.

Derivatives related to betaxolol with α- and β-adrenergic activities

The paper describes the synthesis and the pharmacological evaluation of some derivatives of betaxolol, all with an N-aralkylamine instead of the tertiobutylamine. These compounds have been tested for β1-adrenergic receptor antagonism on guinea pig atria, β2-adrenergic receptor antagonism on guinea pig trachea and α-adrenergic blocking activity on rat aorta. Compound U12 with a marked α-blocking activity and compound R8 with a β1/α ratio = 1 were selected for a haemodynamic study in the dog. The decrease in cardiac work and the diminution of total peripheral resistance exhibited by U12 are consistent with a dual α/β-blocking agent. Finally, structure-activity relationships are discussed.

2-(Arylthio)ethanamines and &α-(Arylthio)propionamides with Antidepressant Activity

Reaction of aziridine with thiophenols affords 2-arylthioethanamines; with 2-methylaziridine, ring opening occurs regiospecifically to provide 1-arylthio-2-propanamines.The structure of one member of this group, 1-(4-chlorophenylthio)-2-propanamine (7), has been proved by other unambiguous syntheses. 7 and isomer 12 arise from the alkylation of 4-chlorothiophenol with 2-chloropropylamine as well as from the displacement of the tosyl group in 1-(4-chlorophenylthio)-2-tosyloxypropane (13).Alkylation of 4-chlorothiophenol with α-chloropropionamide affords 11 which leads to 12 on LAH reduction.Ethanamines and propanamines are converted into guanidines, amides, ureas and thioureas.Many arylthioethanamines, e.g. 7, 22, 28, 38 and 39 (as HCl salts) and α-arylthiopropionamides, e.g. 11, 86, 91, 93 and 96 exhibit good activity in the DOPA potentiation and reserpine antagonism tests.Among these, 7 HCl is the most potent and does not inhibit rat brain MAO activity.In clinical trials, C 2998-Go compares favourably with imipramine.