2349-58-8Relevant articles and documents
Regio- and stereoselective synthesis of thioglycosides from 4,5-diphenyl- and 3,4,5-triphenylimidazole-2-thione
Rezki,Rashed,Awad,Ramadan,Abdel-Maggeed,El Ashry
, p. 1759 - 1767 (2009)
Six new thioglycosides incorporating the 4,5-diphenyl- and 3,4,5-triphenylimidazole moiety have been successfully synthesized under both conventional and microwave conditions by reaction of the corresponding thiones with aceto-bromosugars in presence of t
Efficient Green Synthesis and Computational Chemical Study of Some Interesting Heterocyclic Derivatives as Insecticidal Agents
Fahmy,Rizk,Hemdan,El-Sayed,Hassaballah
, p. 2545 - 2555 (2018/09/27)
A series of 5,5-diarylhydantoin (Dilantin) 3, 4, and 7, imidazole 1, 2, 5, 6, 8, and 9, thiazole 10–12, triazinthione 13, 15, 16, and 17, and thiadiazine 14 derivatives, containing diverse hydrophobic groups, were green synthesized through one-pot stepwise reaction of aromatic aldehydes, vitamin B1, and nitrogen nucleophiles, for example, urea, thiourea, and thiosemicarbazide using grinding technique as well as conventional thermal methods. Such synthesized compounds have potent insecticidal activities; for example, compounds 4, 6, and 17 exhibited the highest insecticidal activity against both Plutella xylostella and Helicoverpa armigera with minimum inhibitory concentration values at 500?μg/mL and LD50 activities at 50?μg/mL. The density functional theory was then applied to explore the structural and electronic characteristics of these compounds. All the synthesized compounds have been characterized based on their elemental analyses and spectral data.
Environmentally benign approach to imidazole 2-thiones
Kidwai, Mazaahir,Kukreja, Shuchi,Rastogi, Shweta,Singhal, Kavita
, p. 1549 - 1553 (2008/09/19)
An ecofriendly synthesis of some novel 1,4,5-triarylimidazole-2-thiones/l, 3,4,5-tetraarylimidazole-2-thiones is described. The reaction involves condensation of benzoin with various readily accessible N-substituted thioureas/N,N'-disubstituted thioureas under microwave over recyclable inorganic solid support. This methodology eliminates the usage of solvent and external catalyst in the reaction step and reduces the reaction time from hours to minutes along with remarkable yield enhancement. In addition versatility of various solid supports as catalyst is also studied.
