23496-56-2

Usage

Uses

Used in Pharmaceutical Industry:
2-amino-1-(2-chlorophenyl)ethanol is used as an antiarrhythmic agent for the management of irregular heartbeats. It functions by blocking specific electrical signals in the heart, thereby stabilizing the heart rhythm and preventing life-threatening arrhythmias.
Used in Pain Management:
Acecainide is utilized as an analgesic to alleviate pain. Its pain-relieving properties make it a candidate for the treatment of various types of pain, including neuropathic pain, which is often challenging to manage with conventional analgesics.
Used in Neurological Treatments:
2-amino-1-(2-chlorophenyl)ethanol has been studied for its potential application in the treatment of epilepsy and other neurological conditions. Its ability to modulate electrical signals in the nervous system suggests a possible role in managing seizure disorders and neuropathic pain.
Used in Chemical Synthesis:
Acecainide may also find use in the synthesis of other pharmaceutical compounds, contributing to the development of new drugs with potentially improved efficacy and reduced side effects.
Used in Research:
As a reagent for chemical reactions, 2-amino-1-(2-chlorophenyl)ethanol aids in various research applications, facilitating the exploration of new chemical pathways and the development of innovative pharmaceutical formulations.

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 89-98-5 2-chloro-benzaldehyde 
• 5000-66-8 2-chlorophenacyl bromide 
• 855300-90-2 C₁₀H₈ClNO₃ 
• 16442-79-8 2-amino-1-(2-chlorophenyl)ethan-1-one hydrochloride 
• 62717-50-4 o-chlorostyrene oxide 
• 85536-83-0 1-(2-chloro-phenyl)-2-nitro-ethanol 
• 13312-84-0 2-chloromandelonitrile 

Downstream Products

• 3811-25-4 clorprenaline 
• 209530-20-1 (+/-)-tert-butyl [2-(2-chlorophenyl)-2-hydroxyethyl]carbamate 

Relevant academic research and scientific papers

Clomaalin hapten and artificial antigen as well as preparation method and application thereof

The invention discloses clobetasine semiantigen and artificial antigen as well as a preparation method and application thereof. sum One of the clomastokinin artificial antigen is obtained by coupling the cloacalin hapten to a carrier protein. The chloropr

Preparation method of stable isotope-labeled clorprenaline

The invention relates to a preparation method of stable isotope-labeled clorprenaline. The preparation method comprises the following steps: with 2-bromo-2'-chloroacetophenone as an initial raw material, successively conducting improved Gabriel synthesis (wherein the initial raw material and an amination reagent sodium, namely diformyl amide are subjected to a nucleophilic substitution reaction), hydrolysis, reduction and reductive amination so as to synthesize the isotope-labeled clorprenaline . According to the preparation method disclosed by the invention, through a four-step conventional chemical reaction, process design is reasonable, raw material price is low, an experimental process is controllable, operation is simple and convenient, various required labeled compounds such as D-labeled, 13C-labeled or D/13C double-labeled compounds can be conveniently synthesized, the purity of the prepared target product is high and reaches 98% or above, total yield reaches 66% or above, the isotope abundance of the final product can reach 98% or above, the phenomenon of isotope abundance dilution is avoided, higher reproducibility and stability are achieved, and the obtained target compound can provide a standard reagent for accurately and quantitatively detecting trace residues of clorprenaline.

Novel 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase

A novel class of 1H-(benzimidazol-2-yl)-1H-pyridin-2-one inhibitors of insulin-like growth factor I (IGF-1R) kinase is described. This report discusses the SAR of 4-(2-hydroxy-2-phenylethylamino)-substituted pyridones with improved IGF-1R potency.