235752-73-5

Basic information

• Product Name: p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D- glucopyranosyl)-a-D-galactopyranoside
• Synonyms: 4-Nitrophenyl2-acetamido-6-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-2-deoxy-a-D-galactopyranoside;p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy--D-glucopyranosyl)-a-D-galactopyranoside;4-Nitrophenyl 2-acetamido-6-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-deoxy-α-D-galactopyranoside;4-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-β-D- glucopyranosyl)-α-D-galactopyranoside;4-Nitrophenyl 2-(acetylamino)-6-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-alpha-D-galactopyranoside;GlcNAc1-b-6GalNAc-α-PNP;4-nitrophenyl 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxyhexopyranosyl]-2-deoxyhexopyranoside
• CAS NO: 235752-73-5
• Molecular Formula: C₂₂H₃₁N₃O₁₃
• Molecular Weight: 545.49
• EINECS: 1533716-785-6
• Product Categories: Oligosaccharides
• Mol File: 235752-73-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 286°C dec.
• Boiling Point: 972.3°C at 760 mmHg
• Flash Point: 541.8°C
• Appearance: /
• Density: 1.55g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.63
• Storage Temp.: -20°C Freezer
• Solubility: Water (Sparingly)
• PKA: 12.73±0.70(Predicted)
• CAS DataBase Reference: p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D- glucopyranosyl)-a-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D- glucopyranosyl)-a-D-galactopyranoside(235752-73-5)
• EPA Substance Registry System: p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D- glucopyranosyl)-a-D-galactopyranoside(235752-73-5)

Safety Data

• Hazardous Substances Data: 235752-73-5(Hazardous Substances Data)

Usage

Chemical Properties

White Crystalline Solid

Uses

Acetylgalactosaminidase sequence substrate Clostridium Bifidobacterium.

InChI:InChI=1/C22H31N3O13/c1-9(28)23-15-18(31)17(30)13(7-26)36-22(15)38-20-14(8-27)37-21(16(19(20)32)24-10(2)29)35-12-5-3-11(4-6-12)25(33)34/h3-6,13-22,26-27,30-32H,7-8H2,1-2H3,(H,23,28)(H,24,29)

Upstream product

• 501088-85-3 ethyl 2-amino-2,3-N,O-carbonyl-2-deoxy-1-thio-β-D-glucopyranoside 
• 1147438-51-4 p-nitrophenyl 3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranoside 
• 100-02-7 4-nitro-phenol 
• 1316823-00-3 p-nitrophenyl 2-azido-3-O-benzoyl-2-deoxy-4,6-O-p-methoxybenzylidene-α-D-galactopyranoside 
• 1316823-01-4 p-nitrophenyl 2-azido-3-O-benzoyl-2-deoxy-α-D-galactopyranoside 
• 1316823-05-8 ethyl 2-amino-4,6-di-O-benzoyl-2,3-N,O-carbonyl-2-deoxy-1-thio-β-D-glucopyranoside 
• 1316823-07-0 ethyl 2-acetamido-4,6-di-O-benzoyl-2,3-N,O-carbonyl-2-deoxy-1-thio-β-D-glucopyranoside 
• 1316823-35-4 p-nitrophenyl 2-acetamido-4,6-di-O-benzoyl-2,3-N,O-carbonyl-2-deoxy-β-D-glucopyranosyl-(1->6)-2-azido-3-O-benzoyl-2-deoxy-α-D-galactopyranoside 
• 210418-04-5 C₁₂H₁₄N₄O₇ 
• 124-41-4 sodium methylate 
• 1316822-99-7 p-nitrophenyl 2-azido-2-deoxy-4,6-O-p-methoxybenzylidene-α-D-galactopyranoside 
• 83025-20-1 3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyltrichloroacetimidate 

Downstream Products

• 1316822-87-3 p-aminophenyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->6)-2-acetamido-2-deoxy-α-D-galactopyranoside 

Relevant articles and documents

Synthesis of mucin O-glycan core structures as their p-nitro- and p-aminophenyl glycosides

For the investigation of glycosidases, and for the construction of glycan arrays the p-nitrophenyl- and p-aminophenyl glycosides of mucin O-glycan core structures 1-7 and the 2,6-ST-antigen have been chemically synthesized using d-galactose as a precursor for GalNAc residues. GlcNAc residues have partly been introduced using a 4,6-di-O-benzoyl-2,3-N,O-oxazolidinone-protected donor, which allowed deprotection of the formed di- and tri-saccharides in one step using sodium methoxide.