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Usage

Uses

Used in Pharmaceutical Industry:
p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D-glucopyranosyl)-a-D-galactopyranoside is used as a substrate for Acetylgalactosaminidase, an enzyme involved in the degradation of certain glycoconjugates. This application is crucial for the development of diagnostic tools and therapeutic strategies for various diseases, including lysosomal storage disorders.
Used in Research and Development:
In the field of research and development, p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D-glucopyranosyl)-a-D-galactopyranoside is used as a valuable tool for studying the structure, function, and mechanisms of Acetylgalactosaminidase and related enzymes. This helps researchers gain a deeper understanding of the biological processes and pathways involving these enzymes, ultimately contributing to the advancement of medical and pharmaceutical sciences.
Used in Quality Control and Validation:
The compound is also utilized in the quality control and validation of Acetylgalactosaminidase assays and tests. By using p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D-glucopyranosyl)-a-D-galactopyranoside as a substrate, researchers and quality control professionals can accurately assess the performance, specificity, and sensitivity of these assays, ensuring the reliability of diagnostic results.
Used in Microbiology:
In the field of microbiology, p-Nitrophenyl 2-Acetamido-2-deoxy-(6-O-2-acetamido-2-deoxy-b-D-glucopyranosyl)-a-D-galactopyranoside is used as a substrate to study the metabolic pathways and enzyme activities of microorganisms such as Clostridium and Bifidobacterium. This information is vital for understanding the role of these microorganisms in various biological processes and their potential applications in biotechnology and pharmaceuticals.

InChI:InChI=1/C22H31N3O13/c1-9(28)23-15-18(31)17(30)13(7-26)36-22(15)38-20-14(8-27)37-21(16(19(20)32)24-10(2)29)35-12-5-3-11(4-6-12)25(33)34/h3-6,13-22,26-27,30-32H,7-8H2,1-2H3,(H,23,28)(H,24,29)

Upstream product

• 83025-20-1 3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyltrichloroacetimidate 
• 1316822-99-7 p-nitrophenyl 2-azido-2-deoxy-4,6-O-p-methoxybenzylidene-α-D-galactopyranoside 
• 124-41-4 sodium methylate 
• 210418-04-5 C₁₂H₁₄N₄O₇ 
• 1316823-35-4 p-nitrophenyl 2-acetamido-4,6-di-O-benzoyl-2,3-N,O-carbonyl-2-deoxy-β-D-glucopyranosyl-(1->6)-2-azido-3-O-benzoyl-2-deoxy-α-D-galactopyranoside 
• 1316823-07-0 ethyl 2-acetamido-4,6-di-O-benzoyl-2,3-N,O-carbonyl-2-deoxy-1-thio-β-D-glucopyranoside 
• 1316823-05-8 ethyl 2-amino-4,6-di-O-benzoyl-2,3-N,O-carbonyl-2-deoxy-1-thio-β-D-glucopyranoside 
• 1316823-01-4 p-nitrophenyl 2-azido-3-O-benzoyl-2-deoxy-α-D-galactopyranoside 
• 1316823-00-3 p-nitrophenyl 2-azido-3-O-benzoyl-2-deoxy-4,6-O-p-methoxybenzylidene-α-D-galactopyranoside 
• 100-02-7 4-nitro-phenol 
• 1147438-51-4 p-nitrophenyl 3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranoside 
• 501088-85-3 ethyl 2-amino-2,3-N,O-carbonyl-2-deoxy-1-thio-β-D-glucopyranoside 

Downstream Products

• 1316822-87-3 p-aminophenyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1->6)-2-acetamido-2-deoxy-α-D-galactopyranoside 

Relevant academic research and scientific papers

Synthesis of mucin O-glycan core structures as their p-nitro- and p-aminophenyl glycosides

For the investigation of glycosidases, and for the construction of glycan arrays the p-nitrophenyl- and p-aminophenyl glycosides of mucin O-glycan core structures 1-7 and the 2,6-ST-antigen have been chemically synthesized using d-galactose as a precursor for GalNAc residues. GlcNAc residues have partly been introduced using a 4,6-di-O-benzoyl-2,3-N,O-oxazolidinone-protected donor, which allowed deprotection of the formed di- and tri-saccharides in one step using sodium methoxide.