2358-54-5

Basic information

• Product Name: 2-(2,2,2-TRIFLUOROETHOXY)ETHANOL
• Synonyms: 2-(2,2,2-TRIFLUOROETHOXY)ETHANOL;2-(2,2,2-Trifluoroethoxy)ethanol97+%;Ethanol, 2-(2,2,2-trifluoroethoxy)-;2-(2,2,2-Trifluoroethoxy)ethan-1-ol 97+%;5,5,5-Trifluoro-3-oxapentan-1-ol, 5-Hydroxy-1,1,1-trifluoro-3-oxapentane;2-(2,2,2-Trifluoroethoxy)ethan-1-ol
• CAS NO: 2358-54-5
• Molecular Formula: C₄H₇F₃O₂
• Molecular Weight: 144.09
• Product Categories: Aliphatics
• Mol File: 2358-54-5.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 84/80mm
• Flash Point: 70 °C
• Appearance: /
• Density: 1.254 g/cm³
• Vapor Pressure: 3.7mmHg at 25°C
• Refractive Index: 1.343
• Storage Temp.: Hygroscopic, Room Temperature, under inert atmosphere
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• PKA: 14.21±0.10(Predicted)
• CAS DataBase Reference: 2-(2,2,2-TRIFLUOROETHOXY)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2,2-TRIFLUOROETHOXY)ETHANOL(2358-54-5)
• EPA Substance Registry System: 2-(2,2,2-TRIFLUOROETHOXY)ETHANOL(2358-54-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 2358-54-5(Hazardous Substances Data)

Usage

General Description

2-(2,2,2-TRIFLUOROETHOXY)ETHANOL is a chemical compound with the molecular formula C4H7F3O2. It is a colorless liquid with a fruity odor. 2-(2,2,2-TRIFLUOROETHOXY)ETHANOL is used as a solvent in various industrial applications, including as a solvent for adhesives, inks, and coatings. It is also used as a chemical intermediate in the production of other compounds. 2-(2,2,2-TRIFLUOROETHOXY)ETHANOL is known to be flammable and should be handled with care. Additionally, it may have potential health hazards if not used properly.

InChI:InChI=1/C4H7F3O2/c5-4(6,7)3-9-2-1-8/h8H,1-3H2

Upstream product

• 75-21-8 oxirane 
• 75-89-8 2,2,2-trifluoroethanol 
• 96-49-1 [1,3]-dioxolan-2-one 
• 311-28-4 tetra-(n-butyl)ammonium iodide 
• 1098411-87-0 2-tetrahydropyran-2-yloxyethyl 2,2,2-trifluoroethyl ether 
• 252947-89-0 tert-butyl 2-(2,2,2-trifluoroethoxy)acetate 

Downstream Products

• 1255707-52-8 methyl 4-bromo-3-(2-(2,2,2-trifluoroethoxy)ethoxy)benzoate 
• 252947-90-3 2-(2, 2, 2-trifluoroethoxy)ethyl 4-methylbenzenesulfonate 
• 1537-70-8 5-chloro-1,1,1-trifluoro-3-oxapentane 

Relevant articles and documents

Synthesis of new fluorine-containing room temperature ionic liquids and their physical and electrochemical properties

An improved synthesis of fluorine-containing room temperature ionic liquids (FRTILs) is described. Twelve FRTILs are synthesized, in which the fluorinated cations based on N-methyl pyrrolidinium (MPy), 1-methly imidazolium (MIm) and diethylsulfide (DES) a

Polymeric 19F MRI Contrast Agents Prepared by Ring-Opening Metathesis Polymerization/Dihydroxylation

The capability of ring-opening metathesis polymerization (ROMP) to efficiently incorporate bulky monomers and conserve olefin bonds during polymerization was exploited to design water-soluble fluoropolymers, which were evaluated as potential quantitative 19F magnetic resonance imaging (MRI) contrast agents. The fluoromonomeric units comprised 3, 6, 9, or 18 magnetically equivalent fluorine atoms. Aqueous solubility was achieved through dihydroxylation of the partially unsaturated polymeric backbone and by tetraethylene glycol (TEG)-based linker incorporation, ammonium quaternization, or copolymerization.

Glucopyranosyl derivative and application thereof in medicines

The invention relates to a glucopyranosyl derivative used as a sodium-dependent glucose transporter (SGLT) inhibitor, a medicinal composition containing the derivative, and an application of the derivative and the medicinal composition in medicines, and especially relates to the glucopyranosyl derivative represented by formula (I) or a pharmaceutically acceptable salt or all stereoisomers thereof, or the medicinal composition containing the derivative, and a use of the derivative and the medicinal composition in the preparation of medicines for treating diabetes and diabetes related diseases.