23597-23-1Relevant articles and documents
Synthesis, molecular docking, and apoptogenic efficacy of novel N-heterocycle analogs to target B-cell lymphoma 2/X-linked inhibitors of apoptosis proteins to regress melanoma
Zabiulla, Zabiulla,Malojirao, Vikas H.,Mohammed, Yasser Hussein Eissa,Thirusangu, Prabhu,Prabhakar,Khanum, Shaukath Ara
, p. 1132 - 1160 (2019/06/17)
The novel series of piperidine conjugated benzophenone analogs with amide link 11a–l were synthesized in a multistep process. The structures of these compounds were confirmed by IR, 1H, 13C, NMR, and mass spectra and also by elementa
Synthesis and evaluation of novel benzophenone-thiazole derivatives as potent VEGF-A inhibitors
Prashanth,Thirusangu, Prabhu,Vijay Avin,Lakshmi Ranganatha,Prabhakar,Khanum, Shaukath Ara
, p. 274 - 283 (2015/02/19)
A series of 2-(4-benzoyl-phenoxy)-N-(4-phenyl-thiazol-2-yl)-Acetamides (10a-n) were synthesized by multistep reaction sequence and all the compounds were well characterized for structural elucidation. The in vitro cytotoxicity of compounds 10a-n was evaluated against EAC and DLA cell lines using trypan blue dye exclusion method. Further MTT assay and LDH release assay, followed by in vivo studies on murine model were also evaluated. The compound 10h with a methyl and fluoro groups at benzophenone moiety and methoxy group at phenyl ring was in a leading position to exhibit the promising antiproliferative effect through translational VEGF-A inhibition.
Significant promoting effects of Lewis acidity on Au-Pd systems in the selective oxidation of aromatic hydrocarbons
Liu, Hongli,Li, Yingwei,Jiang, Huanfeng,Vargas, Carolina,Luque, Rafael
supporting information, p. 8431 - 8433 (2012/10/29)
An unprecedented synergistic effect, obtained for rationally designed Au-Pd alloy nanoparticles supported on an acidic metal-organic framework (MOF), in the aerobic oxidation of the primary C-H bonds in toluene and derivates is reported.