3034-79-5

Usage

InChI:InChI=1/C16H14O4/c1-11-7-3-5-9-13(11)15(17)19-20-16(18)14-10-6-4-8-12(14)2/h3-10H,1-2H3

Upstream product

• 95-49-8 2-methylchlorobenzene 
• 933-88-0 ortho-toluoyl chloride 
• 98-88-4 benzoyl chloride 
• 16331-45-6 p-ethylbenzoyl chloride 
• 28788-62-7 4-butylbenzoyl chloride 
• 1711-06-4 3-Methylbenzoyl chloride 

Downstream Products

• 118-90-1 ortho-methylbenzoic acid 
• 6639-40-3 1,2-bis(2-chlorophenyl)ethane 
• 23597-23-1 2-methyl-benzoic acid o-tolyl ester 
• 4281-17-8 2,2'-(ethane-1,2-diyl)bisbenzoic acid 
• 51908-28-2 2-(β-cyanoethyl)benzoic acid 
• 87-41-2 2-benzofuran-1(3H)-one 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 89-98-5 2-chloro-benzaldehyde 
• 1174895-52-3 2-(2'-methyl-[1,1'-biphenyl]-2-yl)pyridine 
• 1333261-95-2 4-chlorobutyl 2-methylbenzoate 
• 643-58-3 2-methylbiphenyl 
• 1361119-71-2 5-phenyl-2-(o-tolyl)-2H-tetrazole 
• 5448-38-4 N-benzyl-2-methylbenzamide 
• 104847-07-6 N-tert-butyl-2-methyl-benzamide 

Relevant academic research and scientific papers

An unprecedented cobalt-catalyzed selective aroylation of primary amines with aroyl peroxides

A novel and facile cobalt-catalyzed selective aroylation of primary amines with aroyl peroxides was developed for the synthesis of aryl amides. It was unprecedented that C[sbnd]N bond formation product was selectively generated without the common N[sbnd]O bond formation product. Aroyl peroxides act as the sole aroylation reagent without additional base or oxidant. The reactions proceeded under mild conditions and showed broad substrates scope with a series of primary amines and aroyl peroxides.

Uncatalyzed, on water oxygenative cleavage of inert C-N bond with concomitant 8,7-amino shift in 8-aminoquinoline derivatives

Oxygenative cleavage of an inert CAr-NH2 bond with concomitant 1,2 amine migration in 8-aminoquinoline derivatives is reported in water at room temperature. The reaction is highly atom- and step-economical as both C- and N-containing fragments of the C-N bond cleavage are incorporated into the target molecule and is effected without the need for N-oxide. The reaction is scalable to gram level, and the products are useful as electrophilic partners for coupling reactions, ligands in catalysis and bioactive compounds.

Convenient peripheral aroyloxylation reactions of porphyrins and chlorophyll-a-based chlorins with benzoyl peroxide

A practical and efficient methodology for the formation of C-O bonds on the porphyrin/chlorin periphery was developed. The aroyloxy-substituted porphyrins and chlorins related to chlorophyll-a at the β- and meso-positions, respectively, were conveniently synthesized by the free radical substitution reaction with benzoyl peroxide and its homologs.

Copper-catalyzed Csp3-O cross-coupling of unactivated alkyl halides with organic peroxides

An efficient Cu-catalyzed Csp3-O coupling of peroxides with haloalkanes is described. High yields of products were achieved under mild conditions. Significantly, in addition to primary alkyl halides, secondary alkyl halogenated hydrocarbons could also be applied to this system. The new reaction system could tolerate a wide range of organic peroxides.

Convenient peripheral aroyloxylation reactions of porphyrins and chlorophyll-a-based chlorins with benzoyl peroxide

A practical and efficient methodology for the formation of C-O bonds on the porphyrin/chlorin periphery was developed. The aroyloxy-substituted porphyrins and chlorins related to chlorophyll-a at the β- and meso-positions, respectively, were conveniently synthesized by the free radical substitution reaction with benzoyl peroxide and its homologs.

Palladium(II)-catalyzed othro-C-H-benzoxylation of 2-arylpyridines by oxidative coupling with aryl acylperoxides

A palladium(II)-catalyzed ortho-benzoxylation of 2-arylpyridines with aryl acylperoxides was developed. With pyridyl as directing group, the benzoxylation reaction exhibits remarkable regioselectivity and excellent functional group tolerance, providing the products in up to 87% yield.

Palladium-catalyzed decarboxylative arylation of C-H bonds by aryl acylperoxides

A Pd(OAc)2-catalyzed protocol for decarboxylative arylation of aromatic C-H bond was developed using aryl acylperoxides as inexpensive aryl sources. Substrates containing pyridyl, oxime, and oxazoline groups undergo effectively ortho-selective C-H arylation with excellent functional group tolerance. This arylation should begin by directing-group-assisted cyclopalladation, followed by the reaction of the palladacycle with aryl radicals generated in situ by thermal decomposition of the peroxides.

Preparation of liquid substituted benzoyl peroxide mixtures

A series of alkyl substituted benzoyl peroxide mixtures were synthesised from two or three acid chloride combination in aqueous sodium peroxide and butanone solutions in the presence of 0.5 percent stearyltrimethylammonium chloride. Some of these benzoyl peroxide mixtures were found to be liquids at -10 deg C.