236121-24-7

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 13884-92-9 phenylthiomethyl triphenylphosphonium chloride 

Downstream Products

• 236121-33-8 (E)-3-Ethoxy-4,4,4-trifluoro-1-furan-2-yl-2-phenylsulfanyl-but-2-en-1-ol 
• 236121-31-6 (2E,5E)-2-ethoxy-1,1,1-trifluoro-6-phenyl-3-(phenylthio)hexa-2,5-dien-4-ol 
• 236121-32-7 (E)-2-Ethoxy-1,1,1-trifluoro-7,7-dimethyl-3-phenylsulfanyl-oct-2-en-5-yn-4-ol 
• 236121-30-5 (E)-5-Ethoxy-6,6,6-trifluoro-2,2-dimethyl-4-phenylsulfanyl-hex-4-en-3-ol 
• 236121-58-7 (2E,5Z)-2-ethoxy-1,1,1-trifluoro-7,7-dimethyl-3,5-bis(phenylthio)-4-(trifluoromethyl)octa-2,5-dien-4-ol 
• 236121-60-1 (Z)-2,2-diethoxy-1,1,1-trifluoro-4-phenyl-3-(phenylthio)but-3-ene 
• 236121-42-9 (Z)-1,1,1-trifluoro-4-phenyl-3-(phenylthio)but-3-en-2-one 
• 236121-43-0 (Z)-1,1,1-Trifluoro-5,5-dimethyl-3-phenylsulfanyl-hex-3-en-2-one 
• 253670-75-6 (E)-2-ethoxy-1,1,1-trifluoro-6,6-dimethyl-3-(phenylsulfonyl)hept-2-en-4-yne 

Relevant academic research and scientific papers

Direct lithiation and alkylation of trifluoromethyl enol ethers having a β-sulfur substituent

The direct lithiation and alkylation of β-sulfur-α-trifluoromethyl substituted enol ethers 1 - 3 proceeded to give the alkylated products 4a - f, 5, 6a - c in moderate to high yields.

Novel perfluoroacyl olefinations of aldehydes using β-thio-substituted perfluoroalkyl enol ethers

α-(Methylthio)- or α-(phenylthio)-substituted perfluoroacylolefinations of nonenolizable aldehydes using the β-lithio-β- thio-perfluoroalkyl enol ethers 1-4 stereoselectively proceeded to give (Z)- α,β-unsaturated perfluoroalkyl ketones 9a-e, 10a-c, 11a-c, and 12a. The α- (thio)-α,β-unsaturated trifluoromethyl ketones were easily converted to 3- (thio)-2-(trifluoromethyl)-1,3-butadienes 21a-c and 22a,b in moderate to high yields (41-85%).