23616-35-5

Usage

Uses

Used in Pharmaceutical Industry:
1,6-NAPHTHYRIDINE, 2,5-DICHLOROis used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 1,6-NAPHTHYRIDINE, 2,5-DICHLOROserves as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye and Pigment Production:
1,6-NAPHTHYRIDINE, 2,5-DICHLOROis utilized in the creation of dyes and pigments, providing a wide range of color options for various applications, including textiles, plastics, and printing inks.
Used in Specialty Chemicals:
1,6-NAPHTHYRIDINE, 2,5-DICHLOROis also employed in the production of specialty chemicals, where its unique properties can be harnessed for specific industrial applications, such as in the development of advanced materials and coatings.

Upstream product

• 23616-31-1 1,6-naphthyridine-5(6H)-one 
• 23616-32-2 5-chloro-[1,6]naphthyridine 

Relevant academic research and scientific papers

Wnt SIGNALING INHIBITOR, COMPOSITION, AND COMPOUND AS USE THEREFOR

PROBLEM TO BE SOLVED: To provide an inhibitor for Wnt signaling route. SOLUTION: The present invention provides a compound represented by formula I, and a composition comprising the compound (X1-X8 independently represent CR4 or N; Y1 is H or C (R4)3; Y2 and Y3 independently represent H, halogen or C (R3)3; R1 and R2 independently represent H, halogen, C1-6 alkyl, quinolinyl or the like; R3s independently represent H, halogen, cyano, C1-6 alkyl or the like; R4s independently represent H, halogen, cyano, C1-6 alkoxy or the like). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

Inhibiting WNT signal conduction of compound, composition and use thereof (by machine translation)

The invention relates to a having the general formula (1) compounds and compositions thereof, and the use of the compound or composition thereof to inhibit WNT signal transmission method. The compounds of this invention and its composition can effectively inhibit the secretion of WNT protein, inhibit WNT signal conduction, so the WNT-mediated disease with a very good therapeutic effect. . (by machine translation)

TUMOR BIOMARKERS AND USE THEREOF

Disclosed herein are biomarkers related to WNT signal transduction pathway, as well as methods and kits comprising the same. Further, the present disclosure relates to the use of the biomarkers in patient selection, companion diagnostics, and treatment of cancer.

Compound as WNT Signaling Inhibitor, Composition, and Use Thereof

The present invention relates to a compound having the structure of Formula I as inhibitor of WNT signal transduction pathways, as well as a composition comprising the compound. Further, the present invention relates to the use of the compound and the method of inhibiting the WNT signal transduction pathways.

COMPOUNDS FOR TREATMENT OF CANCER

The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present invention relates to the use of the compounds in the treatment of cancer.

COMPOUNDS FOR TREATMENT OF FIBROSIS DISEASES

The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present invention relates to the use of the compounds in the treatment of fibrosis. Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. Fibrosis is the end result of chronic inflammatory reactions induced by a variety of stimuli including persistent infections, autoimmune reactions, allergic responses, chemical insults, radiation, and tissue injury.

COMPOUND AS WNT SIGNALING INHIBITOR, COMPOSITION, AND USE THEREOF

The present invention relates to a compound having the structure of Formula I as inhibitor of WNT signal transduction pathways, as well as a composition comprising the compound. Further, the present invention relates to the use of the compound and the method of inhibiting the WNT signal transduction pathways.